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A protein called CBP is found in prostate cancer and can increase the effectiveness of certain prostate cancer treatments.

New genes and pathways are important for testosterone production and male sexual development.

Finasteride reduces hairiness and androgen levels in women with unexplained excessive hair growth.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Docetaxel and paclitaxel for breast cancer can cause permanent, severe hair loss.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Cyclosporin A helps mice grow hair by blocking a specific protein activity in skin cells.

Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.

Giving docetaxel weekly at 40 mg/m² is manageable and has low toxicity for cancer patients.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

Tumor suppressors help control inflammation in cancer and restoring their function could lead to new treatments.

Genetic mutations can cause hair growth disorders by affecting key genes and signaling pathways.

No consistent link between genotype and phenotype in 5-α-Reductase type 2 deficiency.

Herbs can potentially treat hair loss by inhibiting a key enzyme and promoting hair growth, and deficiencies in zinc, biotin, and iron are linked to hair loss.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Hair proteins have weak spots in their α-helical segments.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

pH, calcium, and reactive oxygen species regulate plant cell growth, with key roles for NADPH oxidases and plasma membrane H+-ATPases.

Scalp melanomas are more dangerous and often missed, needing earlier detection.

Apple-derived procyanidin B-2 can safely promote hair growth in men.

LPA3 is crucial for embryo implantation and links LPA to prostaglandin signaling.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Red spots on fingertips can be a sign of a skin condition linked to gluten sensitivity, treatable with a gluten-free diet.

Hair disorders are caused by a complex mix of biology, genetics, hormones, and environmental factors, affecting hair growth and leading to conditions like alopecia.

The article concludes that the global hair trade is exploitative and reflects complex cultural and economic issues.

Thymosin β4 helps improve skin healing and reduce scarring.

Suppressing certain hormones might help prevent prostate cancer.

Certain microRNAs are linked to various skin diseases and could be used to diagnose and treat these conditions.

Hair regrowth slows with age and can be affected by treatments that change enzyme activity in the skin.