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This study showed that Thujae occidentalis semen extract inhibited 5alpha-reductase type 2 in laboratory tests and reduced androgen-related hair loss in animal models, suggesting potential use for male pattern baldness.

This study found that a 532 nm laser at 15 J/cm² enhanced the proliferation and differentiation of tendon-derived stem cells in rats, potentially accelerating tendon healing through the up-regulation of Nr4a1.

In this study, researchers presented a novel therapeutic approach for androgenetic alopecia combining AR-PROTAC degradation with regenerative strategies and evaluated the potential of GT20029 as a topical treatment, proposing a three-phase protocol and future research hypotheses.

The researchers reported two brothers with a new variant of X-linked trichothiodystrophy associated with an RNF113A gene mutation, highlighting features such as intellectual disability and growth failure, but without previously reported endocrinological or genital abnormalities, underlining the importance of genetic counseling for such variants.

This study found that certain gene sets, including those involved in ligand-gated ion channel signaling and cell adhesion, are associated with Tourette syndrome, suggesting a potential neurobiological basis for the disorder.

In this study, researchers identified and examined males with 17 beta-HSD3 deficiency in a highly inbred Arab population, noting genetic findings and the progression of male characteristics despite being raised as females initially.

TCHHL1 is a protein important for hair growth, found in hair follicles.

This study found that locally injected zalutumumab in healthy volunteers induced a papulopustular rash similar to systemic EGFR inhibitors, and that IL-8 inhibition reduced this dermatological side effect.

In this study, researchers discovered that activating TERT in mouse skin epithelium triggers dormant hair follicle stem cells, leading to rapid hair growth, through a pathway independent of telomere extension.

This study developed a multifunctional 3D-printed hydrogel scaffold, SH-EGCG, that showed promising results for repairing infected diabetic wounds; in lab and animal tests, it demonstrated antibacterial activity, enhanced wound healing, and improved tissue regeneration and remodeling through various supportive mechanisms.

This study identified a germline variant in PLCD1 as a major risk allele for familial trichilemmal cysts, requiring a subsequent somatic mutation in the same allele for cyst formation.

This study found that the penta-peptide Gly-Pro-Ile-Gly-Ser increased the proportion of thick hair and improved baldness appearance in Japanese men with androgenetic alopecia.

Scientists turned rat thymus cells into stem cells that can help repair skin and hair.

This pilot study suggests that skin-resident γδT-cells may play a significant role in the early stages of alopecia areata pathogenesis, indicating a potential new target for therapeutic management.

This study found that mutations in the TMPRSS6 gene affect the ability of matriptase-2 to inhibit hepcidin, which may impact the molecular pathogenesis of iron-refractory iron-deficiency anemia.

This study identified ten key hub genes and pathways crucial for understanding the molecular mechanism of hair growth by comparing dermal papilla cells in 2D and 3D cultures.

This study found that keratin 19 and nuclear galectin-1 binding can transiently express in interfollicular epidermal cells after adhesion, suggesting keratin 19 should not be solely used as a stem cell activity marker.

In this study, a taurine-based ionic liquid was developed to effectively penetrate the skin barrier and deliver antioxidants to hair follicles, reducing oxidative stress and promoting hair regrowth in an androgenic alopecia animal model.

This pilot study found that growth factor concentrate therapy improved hair growth in patients with androgenetic alopecia, was well tolerated, and achieved high patient satisfaction.

This study reports a novel TRbeta gene mutation associated with resistance to thyroid hormone syndrome, which may contribute to various forms of alopecia in the affected family members.

This study found that human dermal γδT-cells can act as stress sentinels and potentially trigger autoimmune responses toward stressed hair follicles, resembling features of alopecia areata.

This study investigated peptidergic nerve fibers in sinus hair follicles of various mammals and found that CGRP fibers were more densely distributed than SP fibers across different regions of the follicles.

This study suggests that Tenebrio molitor larvae extract may promote hair growth and prevent hair loss by enhancing cell proliferation and protecting against cytotoxicity in laboratory settings.

This study reported that black hairy tongue can occur after allogeneic stem cell transplantation and may indicate cutaneous graft-versus-host disease, highlighting the need for histopathologic evaluation.

This study suggests that increased amounts of less stable disulfide conformers in hair shafts may be linked to the brittleness observed in trichothiodystrophy.

This study found that 18-β-Glycyrrhetinic acid, a licorice component, stimulated human hair follicle cell proliferation, inhibited testosterone 5α-reductase, and suppressed TGF-β1, suggesting potential for treating androgenetic alopecia by promoting hair growth and prolonging the anagen phase.