1 citations
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February 2013 in “Steroids” In this study, a deproteinized bone mineral showed potential to increase DHT production, suggesting an anabolic effect on human periosteal fibroblasts with possible implications for wound healing.
February 2015 in “Oxford University Press eBooks” This article discusses various aspects of sex steroid production and physiology in men, along with a clinical case of primary amenorrhoea, but reports no new research findings.
April 2021 in “Journal of evolution of medical and dental sciences” This study found that bioavailable testosterone and the free androgen index were significantly associated with various clinical and biochemical features of PCOS, including hirsutism, showing higher levels in PCOS patients compared to controls.
16 citations
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January 2000 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” This study found that serum PSA levels are higher in hirsute women and can be significantly reduced by antiandrogen treatment, suggesting PSA as a marker of androgen action in females.
January 2004 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study found no elevation of serum DHEA-S levels in men with androgenetic alopecia and observed no correlation between DHEA-S levels and the clinical stage of the condition.
56 citations
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October 1983 in “Archives of Dermatology” This study found that free testosterone levels were a more sensitive indicator of hyperandrogenism in women with acne than total testosterone levels.
7 citations
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January 2018 in “Australian Prescriber” This review discusses the presence of undeclared substances, including androgenic steroids, in sports supplements and emphasizes potential health risks, without providing new results; it advises caution and consultation on supplement use.
21 citations
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December 1977 in “Journal of pediatric surgery” The authors concluded that most male pseudohermaphrodites should be raised as females, recommending early gender assignment and appropriate alterations to better support coping and development.
June 2023 in “Journal of personalized medicine” This study found that dihydrotestosterone treatment may be more beneficial for height in children with 5-α-reductase type 2 deficiency compared to testosterone enanthate, especially in the prepubertal period.
October 2019 in “European heart journal” This study found that androgen deprivation therapy is associated with an increased risk of acquired long-QT syndrome and Torsades de Pointes, particularly highlighting enzalutamide's greater association with sudden death compared to other therapies.
123 citations
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December 1997 in “Calcified Tissue International” This study concluded that higher androgen levels in males and specific skeletal sites may contribute to differences in skeletal morphology, with glucocorticoids, E2, and D3 enhancing androgen receptor expression and mitogenic action in human osteoblastic cells.
11 citations
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September 2015 in “Theriogenology” Testosterone boosts fluid and electrolyte secretion in seminal vesicles, aiding sperm function.
2 citations
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January 2021 in “Cureus” This case report examines the long-term impact of extensive anabolic-androgenic steroid use on metabolic and cardiovascular health, highlighting adverse effects to guide primary care for this patient group.
January 2011 in “Journal of pediatric endocrinology & metabolism/Journal of pediatric endocrinology and metabolism” This case study reported hyperandrogenism in non-obese triplet sisters with one sister's hyperthyroidism masking its clinical and biochemical signs until treatment increased her androgen levels and hirsutism.
82 citations
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February 1989 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” This study found that in men with benign prostatic hyperplasia, a 3-month treatment with a long-acting GnRH agonist significantly reduced intraprostatic DHT and 3α-diol levels by about 90% and testosterone by about 75%.
46 citations
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May 2012 in “Molecular and Cellular Endocrinology” In this study, higher expression levels of aromatase and steroidogenic acute regulatory protein were correlated with increased estrogen synthesis and fewer hair follicles in human skin, suggesting a link to elastic fiber formation and hair growth.
July 2022 in “International Journal of Health Sciences” This study assessed lipid parameters and serum DHT levels in type 2 diabetes patients, but the abstract does not specify the findings about their association.
November 2022 in “Journal of the Endocrine Society” This case report highlights the diagnostic challenge of identifying androgen-secreting ovarian Leydig cell tumors in postmenopausal women when imaging fails to reveal masses, emphasizing the usefulness of ovarian vein sampling for localization.
22 citations
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May 1986 in “Clinics in endocrinology and metabolism” This study found that women with lower 2D:4D ratios and fewer middle-phalangeal hairs reported more adverse side effects from oral contraceptives, suggesting these features may predict hormonal contraceptive side effects.
20 citations
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January 2003 in “Treatments in Endocrinology” Testosterone therapy can help improve mood, sexual function, and bone health in women with low androgen levels, but more research is needed to establish safe and effective guidelines.
7 citations
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March 2023 in “Gynecological Endocrinology” This study reported a rare case of ovarian steroid cell tumor removal resulting in normalized hormone levels, resumption of menstruation, and subsequent spontaneous pregnancy in a 31-year-old woman.
September 2020 in “Benha Journal of Applied Sciences” In this study, researchers found that serum Myostatin levels and HOMA-IR were significantly higher in patients with androgenic alopecia compared to controls, suggesting they could be indicators of disease susceptibility and severity.
January 2021 in “touchREVIEWS in Endocrinology” Surgery successfully treated a hidden ovarian tumor causing hair loss and excess hair growth in a postmenopausal woman.
41 citations
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January 2000 in “Hormone Research in Paediatrics” In this case study, a 55-year-old woman with androgenetic alopecia was ultimately diagnosed with hepatic cortisone reductase deficiency after initially suspected 21-hydroxylase deficiency was ruled out.
20 citations
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January 2007 in “Fertility and Sterility” This case report highlights that a postmenopausal woman experienced virilization due to unintentional transdermal absorption of testosterone from her spouse's topical androgen via shared washcloths, underscoring the importance of considering exogenous androgen exposure in similar diagnoses.
10 citations
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March 2008 in “DMW - Deutsche Medizinische Wochenschrift” In this case report, a man developed loss of libido, decreased hair growth, and gynecomastia after using an estrogen-containing hair tincture, but symptoms resolved and hormone levels normalized after he stopped using it.
February 2014 in “Revista Argentina de Cardiología” In this study, testosterone was found to increase the risk of arrhythmias in a rat heart model, while finasteride reduced this arrhythmogenic effect.
This study found that finasteride significantly reduced prostate weight and DHT levels in male mastomys, but not in females, suggesting unique androgen metabolism in female prostates.
July 2022 in “International Journal of Health Sciences (IJHS) (En línea)” In this study, researchers found that serum dihydrotestosterone levels were significantly lower in individuals with Type 2 Diabetes compared to healthy controls, with 90% of diabetics displaying subnormal levels.