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Some antiandrogens may lower testosterone better than others, but it's unclear which is best for feminization in transgender women; more research is needed.

Human beard hair follicles change testosterone into other related hormones, but don't much change androstenedione into testosterone.

Testosterone therapy may slightly improve sexual function in postmenopausal women, but its long-term safety is unknown.

Testosterone is made by Leydig cells, is active when not bound to proteins, and works by binding to receptors in muscles and other tissues.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

Testosterone and its byproducts help support male sexual behavior through different pathways in the brain and body.

Testosterone therapy can improve sexual desire and function in postmenopausal women but should be used cautiously and not based solely on testosterone levels.

Testosterone therapy and surgeries like mastectomy improve transgender men's lives and mental health with low risks and high satisfaction.

Testosterone affects hair follicles differently across body sites, with beard hair follicles showing more activity of a specific enzyme and presence of androgen receptors compared to scalp hair.

Testosterone treatment in transgender teens can worsen acne, requiring careful treatment due to mental health and medication side effects.

Certain SHBG gene variants, like rs727428, are linked to higher testosterone levels in women with PCOS.

The substance MK386 effectively blocked testosterone conversion and reduced cell growth in certain skin cells, but inhibiting 5α-reductase alone may not greatly improve acne.

Androgens, male hormones, play a role in both men and women's health, and testosterone therapy can help women with low levels, but it's not suitable for pregnant or lactating women, or those with certain conditions.

These drugs cause hair growth without affecting testosterone or adrenal hormones.

New and future treatments for male hypogonadism include various forms of testosterone therapy and emerging drugs.

Hormone therapy with estradiol and spironolactone can regrow scalp hair in transgender women by lowering testosterone to female levels.

Researchers found potential urine markers for polycystic ovary syndrome, including testosterone-glucuronide and 11α-hydroxyprogesterone, which may help diagnose the condition.

Oophorectomy lowers testosterone and estrogen levels in both premenopausal and postmenopausal women, with postmenopausal women still producing significant testosterone.

Some new progesterone derivatives are better at blocking testosterone conversion than a common drug.

Finasteride reduces dihydrotestosterone, increases testosterone, and may treat hirsutism in women.

Chromium supplements don't improve insulin, hormone levels, or cholesterol in women with PCOS but raise testosterone levels.

Nearly half of the studied men with long COVID had low testosterone, including younger men.

A woman developed male traits from accidental contact with her husband's testosterone gel.

Testosterone therapy can help improve mood, sexual function, and bone health in women with low androgen levels, but more research is needed to establish safe and effective guidelines.

Sex hormones like estrogen and testosterone may affect COVID-19 severity differently in men and women, potentially influencing prevention and treatment strategies.

Testosterone therapy helps boys with hormone deficiencies develop normal male characteristics and grow properly.

The document concludes that careful evaluation is needed to diagnose PCOS correctly due to similar symptoms in other conditions, and accurate testosterone level measurement is crucial.

Curcumin and its derivatives can block an enzyme important for making testosterone, with one derivative being particularly strong.

Male rats have more somatostatin neurons than females due to testosterone converting to estrogen during early development.

Sex hormones may affect COVID-19 severity, with estrogen possibly reducing risk and testosterone potentially increasing it.