Scalp Hair Regrowth in Hormone-Treated Transgender Woman

The document reports a case of a 33-year-old transgender woman experiencing scalp hair regrowth after undergoing hormone therapy with oral estradiol and spironolactone for 6 months, which resulted in testosterone levels within the normal female range. Initially presenting with male pattern baldness, the patient's hormone therapy was adjusted over a year until her testosterone levels reached 11 ng/dL and estradiol levels were at 92 pg/mL. The treatment not only reduced male-pattern hair distribution but also reversed the effects of androgen on scalp hair patterns. The case suggests that achieving scalp hair regrowth in transgender women is possible through the suppression of testosterone to normal female levels, typically requiring therapy with both spironolactone and estradiol. The document emphasizes the potential of hormone therapy to address androgenetic alopecia in transgender women, aligning physical appearance more closely with gender identity.