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Blood tests can detect ovarian Leydig cell tumors when scans don't, and surgery can confirm and treat these tumors.

HNG may help prevent the negative effects of chemotherapy on sperm production and white blood cell counts.

The document concludes that Borrelia afzelii causes a skin condition in France, a gene is linked to hair loss in Caucasian women, and various genetic mutations affect skin diseases.

Early detection and comprehensive treatment of PCOS are crucial due to its long-term health impacts and associated risks.

The conclusion is that endocrinology significantly impacts medicine with various common medications used for treatment.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

New compounds were made that block an enzyme linked to breast cancer better than existing treatments.

New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.

New hybrid compound found to effectively prevent hair loss.

Idiopathic hirsutism causes excessive hair growth in women, can be treated with medication and hair removal, but cannot be fully reversed.

Anti-androgens are effective for female acne but less so for male-pattern hair loss, with side effects similar to birth control pills.

Compounds 4, 4b, and 4c effectively inhibit an enzyme linked to testosterone conversion without significant toxicity.

Hirsutism is excessive male-pattern hair growth in women, often caused by hormonal imbalances, and requires ongoing treatment to manage.

5α-reductase inhibitors help treat disorders caused by DHT and have potential for future therapies.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Finasteride, a hair loss drug, may cause long-term sexual side effects due to changes in hormone receptor levels.

Using high doses and multiple drugs with steroids is risky and should be prevented.

Using β-cyclodextrin derivatives improves the solubility and bioavailability of steroidal drugs.

There are potential treatments for pattern baldness, but more research is needed to confirm their effectiveness.

Cyproterone acetate effectively treats sexual disorders by reducing sexual functions and is generally well-tolerated.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

The engineered yeast strain BLYAS can quickly and sensitively detect androgenic chemicals.

Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

Grateloupia elliptica extract may help prevent hair loss and promote hair growth.

Hormonal therapies like cyproterone acetate and spironolactone may help some women with hair loss, but finasteride 1mg is not useful, and the effectiveness of other treatments is still unclear.

The document concludes that a systematic approach is crucial to identify causes of androgen excess in women beyond the most common cause, Polycystic ovary syndrome (PCOS).

Letrozole reduces seizures but not brain damage in mice.

DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.

Cyclosporin extends hair growth in mice, but high-dose corticosteroids block this effect.