39 citations,
January 2019 in “The World Journal of Men's Health” Testosterone replacement therapy can prevent men from fathering children and should not be used by those wanting to stay fertile.
2 citations,
September 2017 in “Archives of Medical Science” Finasteride affects offspring's antioxidant enzymes in epididymis, possibly disrupting sperm maturation.
30 citations,
August 1992 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride doesn't affect hormone levels in normal men.
May 1999 in “Drugs & Therapy Perspectives” Finasteride helps increase or maintain hair in most men but can cause sexual side effects and should not be used by women, especially during pregnancy.
688 citations,
June 2007 in “Cell Stem Cell” Removing the ATR gene in adult mice causes rapid aging and stem cell loss.
79 citations,
December 1990 in “Clinical endocrinology” The testes control steroid production through complex interactions involving various cells and signaling molecules.
3 citations,
December 2014 in “Elsevier eBooks” Male hormones and their interactions are crucial for male sexual development and characteristics.
1 citations,
August 2019 in “Journal of pediatric & adolescent gynecology” A new genetic change causing early stop in the androgen receptor gene was found in a patient with androgen insensitivity syndrome.
June 2023 in “Food frontiers” Ginsenoside CK, found in Panax ginseng, can prevent hair loss by controlling certain growth pathways and promoting hair follicle development.
January 2022 in “European journal of anatomy” A man had four testicles, two of which were outside the scrotum and looked like fatty lumps.
Different drugs are used to manage breeding, prevent or end pregnancy, and treat reproductive issues in dogs and cats.
October 2010 in “Journal of Men's Health” Larger prostate size in older men may be linked to poorer semen quality and fertility issues.
February 1990 in “Pathology, research and practice” PCS rats show significant inner ear damage and zinc deficiency, similar to liver cirrhosis patients.
May 2017 in “Endocrine Abstracts” Men with early hair loss and certain health factors may have a higher risk of developing reproductive issues, similar to polycystic ovary syndrome in women.
1 citations,
August 1978 in “Dicp-The annals of pharmacotherapy” A liquid protein diet caused hair loss in a young woman.
June 2018 in “The Journal of Sexual Medicine” Finasteride helps female-pattern hair loss.
101 citations,
April 1994 in “Baillière's clinical endocrinology and metabolism” 5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.
October 2010 in “Journal of Men's Health” Some patients may experience lasting sexual dysfunction, depression, and other side effects from 5α-reductase inhibitor therapy.
227 citations,
January 1998 in “Journal of Endocrinology” Cells from balding scalps have more androgen receptors than cells from non-balding scalps.
165 citations,
December 2002 in “Molecular and Cellular Endocrinology” Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.
110 citations,
April 2002 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Dihydrotestosterone gel improved well-being and sexual function in older men without negatively affecting prostate health.
94 citations,
August 1975 in “Journal of Cutaneous Pathology” Male pattern baldness involves smaller hair follicles, larger oil glands, and other tissue changes, but not major blood supply issues.
92 citations,
November 2003 in “The Journals of Gerontology” Testosterone supplements can increase muscle mass and strength in older men with low levels, but long-term effects and risks need more research.
76 citations,
April 2005 in “Cancer Epidemiology, Biomarkers & Prevention” E211 G>A gene linked to lower risk of severe prostate cancer and hair loss.
60 citations,
February 2013 in “Cell reports” The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.
55 citations,
July 2013 in “Dermatologic therapy” Some dermatological medications can impair male fertility, so consult a doctor before trying to conceive.
41 citations,
August 2007 in “British Journal of Dermatology” Men with Kennedy disease have less chance of hair loss.
37 citations,
January 2009 in “Sexual Development” Fadrozole and Finasteride change frog sex ratios and cause intersex animals with altered gene expressions.
35 citations,
February 1994 in “Fundamental and applied toxicology” High doses of finasteride cause cell growth and tumors in mice.
20 citations,
May 1985 in “British journal of nutrition” Dietary essential fatty acids improved skin and hair conditions and partially corrected fat composition in diabetic mice.