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Glossary Terminal Hair Density

number of thick, pigmented hairs per unit area

Terminal Hair Density refers to the number of thick, pigmented hairs (known as terminal hairs) per unit area of the scalp or other body regions. This measurement is often used in clinical settings to assess hair growth patterns, diagnose hair loss conditions like alopecia, and evaluate the effectiveness of hair restoration treatments.

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The Predictive Value of Midscalp Hair Density and Terminal Hair Percentage in the Severity Evaluation of Female Pattern Hair Loss Assessed by Trichoscan in a Sample of Chinese Population

research The Predictive Value of Midscalp Hair Density and Terminal Hair Percentage in the Severity Evaluation of FPHL Assessed by Trichoscan in a Sample of Chinese Population

1 citations , December 2022 in “Clinical, Cosmetic and Investigational Dermatology”

In this study, TrichoScan characteristics, particularly hair density and terminal hair percentage in the midscalp, were found to predictively classify female pattern hair loss in a Chinese population.

research The Density Issue in Hair Transplantation

32 citations , September 1997 in “Dermatologic Surgery”

This study found that mini-micrografting and plug methods achieve comparable hair density, but mini-micrografting requires fewer sessions due to its dense graft packing.

research Quantitative trichoscopic analysis of hair density in people attending tertiary care hospital – A cross-sectional study

1 citations , August 2024 in “Journal of Cutaneous and Aesthetic Surgery”

In this observational study, hair density was found to vary with age, as measured in subjects from a dermatology outpatient department, with males showing a mean unit density of 104.78 and females 108.36.

The 1,927-nm Fractionated Thulium Laser Monotherapy Increases Hair Density in Patients with Male Pattern Hair Loss in Brazil: Prospective Clinical Study

research The 1,927-nm fractionated thulium laser monotherapy increases hair density in patients with male pattern hair loss in Brazil: prospective clinical study

December 2025 in “Medical Lasers”

This prospective study found that 1,927-nm fractionated thulium laser treatment significantly increased hair and terminal hair counts in 11 men with pattern hair loss, although it did not change average hair thickness, suggesting it may be a promising therapy for this condition.

research Mapping the hair density, thickness, and volume in normal and androgenetic alopecia subjects with the digital microscope

December 2022 in “JEADV Clinical Practice”

In this study, researchers found that using a handheld digital microscope, hair diameter was a better determinant of perceived alopecia severity in androgenetic alopecia than hair density.

research Hair Density in African Americans

129 citations , June 1999 in “Archives of Dermatology”

This study found that hair density is significantly lower in African Americans compared to whites, which may affect the evaluation and diagnosis of scalp biopsy specimens in this population.

The Ludwig Pattern of Androgenetic Alopecia Is Due to a Hierarchy of Androgen Sensitivity Within Follicular Units That Leads to Selective Miniaturization and a Reduction in the Number of Terminal Hairs Per Follicular Unit

research The Ludwig pattern of androgenetic alopecia is due to a hierarchy of androgen sensitivity within follicular units that leads to selective miniaturization and a reduction in the number of terminal hairs per follicular unit

47 citations , September 2008 in “British Journal of Dermatology”

This study found that women with androgenetic alopecia experience diffuse hair loss due to a decrease in terminal hairs and an increase in vellus hairs per follicular unit.

research Hair regrowth in male and female pattern hair loss does not involve the conversion of vellus hair to terminal hair

14 citations , January 2016 in “Experimental Dermatology”

This analysis concluded that hair regrowth in male and female pattern hair loss treatments did not involve converting vellus hairs into terminal hairs, suggesting a reactivation of dormant non-vellus follicles instead.

research Amaranthus Extract Promotes Healthy Follicles and Anagen Hair Density-A Randomized Placebo-Controlled, Double-Blinded Study.

October 2025 in “PubMed”

This study found that applying amaranthus extract cream to the scalp significantly improved terminal hair density, anagen hair count, and pilary index in men with male pattern hair loss, suggesting it may be a safe and effective supportive therapy.

research Hair diameter vs. hair density in male androgenetic alopecia

November 2014 in “British Journal of Dermatology”

Hair loss is due to thinner hairs, not less hairs; hair diameter indicates balding progression and treatment effectiveness.

Mesenchymal Stem Cell-Derived Exosomes Can Effectively Improve Hair Count and Terminal Hair Diameter in Androgenetic Alopecia

research Mesenchymal Stem Cell-Derived Exosomes Can Effectively Improve the Hair Count and Terminal Hair Diameter in Androgenetic Alopecia

June 2025 in “Research Square (Research Square)”

This study reported that intradermal injections of stem cell exosomes appeared safe and significantly improved hair density and diameter in male androgenetic alopecia patients over 24 weeks, suggesting the therapy may be a promising new treatment option worthy of further investigation.

research Clinical Study to Evaluate the Efficacy and Safety of a Hair Serum Product in Healthy Adult Male and Female Volunteers with Hair Fall

14 citations , September 2020 in “Clinical, cosmetic and investigational dermatology”

This study found that a hair serum containing amla extract, freeze-dried coconut water, and selenium significantly improved hair growth rate, density, and reduced hair fall among healthy volunteers over 90 days.

research Efficacy Evaluation of a Novel Home-Used Device Based on a Multiple Stimulation Technology on Hair Growth in Patients with Androgenetic Alopecia

1 citations , August 2018 in “Madridge journal of dermatology & research”

This study observed that the Pilogics Hairegen device increased total hair count by 23.2% and terminal hair count by 21.1% in 289 patients with androgenetic alopecia after approximately 20 weeks of use, with no adverse effects reported.

A 6-Month, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Ability of a Marine Complex Supplement to Promote Hair Growth in Men with Thinning Hair

research A 6-month, randomized, double-blind, placebo-controlled study evaluating the ability of a marine complex supplement to promote hair growth in men with thinning hair

25 citations , August 2016 in “Journal of Cosmetic Dermatology”

This study found that a marine complex supplement significantly reduced hair shedding and increased hair growth in men with thinning hair over 180 days.

research Hair regrowth following a Wnt- and follistatin containing treatment: safety and efficacy in a first-in-man phase 1 clinical trial.

16 citations , November 2011 in “PubMed”

This study found that a single intradermal injection of Hair Stimulating Complex significantly improved hair growth in men with androgenetic alopecia compared to placebo.

QR 678 and QR678 Neo vs PRP—A Randomized, Comparative, Prospective Study

research QR 678 & QR678 Neo Vs PRP—A randomised, comparative, prospective study

14 citations , April 2020 in “Journal of Cosmetic Dermatology”

In this study, intradermal injections of QR678 were found to significantly reduce hair fall in men with androgenetic alopecia over 6 months, with superior improvements in hair density and thickness compared to PRP.

Effects of an Oral Contraceptive Containing Chlormadinone Acetate and Ethinylestradiol on Hair and Skin Quality in Women Wishing to Use Hormonal Contraception

research Effects of an oral contraceptive containing chlormadinone acetate and ethinylestradiol on hair and skin quality in women wishing to use hormonal contraception

6 citations , March 2012 in “Journal of the European Academy of Dermatology and Venereology”

This study found that 12 cycles of chlormadinone acetate in hormonal contraceptives significantly improved oily skin and hair quality, enhancing psychosocial well-being in healthy women.

research Clinical Study to Evaluate the Efficacy and Safety of a Hair Serum Product in Healthy Adult Male and Female Volunteers with Hair Fall

5 citations , September 2020 in “DOAJ (DOAJ: Directory of Open Access Journals)”

This study found that a hair serum containing amla extract, freeze-dried coconut water, selenium, sandalwood odorant, and peanut shell extract significantly improved hair growth, density, and reduced hair fall after 90 days in healthy volunteers.

Commentary on a Randomized Placebo-Controlled, Double-Blind, Half-Head Study to Assess the Efficacy of Platelet-Rich Plasma on the Treatment of Androgenetic Alopecia

research Commentary on a Randomized Placebo-Controlled, Double-Blind, Half-Head Study to Assess the Efficacy of Platelet-Rich Plasma on the Treatment of Androgenetic Alopecia

4 citations , March 2016 in “Dermatologic Surgery”

PRP treatment increased hair density, especially in men and younger patients with AGA.

research Double-Blind, Placebo-Controlled Pilot Study on the Use of Platelet-Rich Plasma in Women With Female Androgenetic Alopecia

3 citations , May 2017 in “Dermatologic Surgery”

PRP may help treat female hair loss, but more research needed.

A Study to Assess the Efficacy of Fractional Carbon Dioxide Laser with Topical Platelet-Rich Plasma in the Treatment of Androgenetic Alopecia

research A study to assess the efficacy of fractional carbon dioxide laser with topical platelet-rich plasma in the treatment of androgenetic alopecia

2 citations , January 2022 in “Lasers in Medical Science”

This pilot study reported significant improvement in hair restoration and patient satisfaction with the use of fractional carbon dioxide laser followed by platelet-rich plasma, showing greater hair density increases using higher laser pulse energy settings in individuals with androgenetic alopecia.

research Platelet-rich plasma in interventional dermatology and trichology: How far have we come?

2 citations , June 2021 in “Cosmoderma”

This article reviews the use of platelet-rich plasma (PRP) in various dermatological conditions and reports no new clinical results; the authors emphasize its efficacy and call for continued careful use.

research Topical cetirizine 1% for treatment of androgenetic alopecia

2 citations , August 2017 in “Dermatologic Therapy”

This letter to the editor discusses the use of topical cetirizine 1% for treating androgenetic alopecia but reports no new clinical outcomes.

research Low-level laser therapy for androgenic alopecia

2 citations , October 2014 in “International Journal of Trichology”

Low-level laser therapy may increase hair density in pattern hair loss.

research Efficacy of Hair Mesotherapy With Biomimetic Peptides and Micronutrients in Patients With Androgenetic Alopecia: A Retrospective Observational Study

June 2026 in “Journal of Cosmetic Dermatology”

This study found that hair mesotherapy containing biomimetic peptides, vitamins, and micronutrients significantly improved hair parameters in patients with androgenetic alopecia and was well-tolerated over an 8-session treatment period.

research Effects of dietary supplements on androgenetic alopecia: a systematic review and network meta-analysis

January 2026 in “Frontiers in Nutrition”

This study found that various dietary supplements positively impacted hair density and were well-tolerated among patients with androgenetic alopecia, suggesting they may be useful adjuncts or alternatives to standard treatments.

Uncontrolled Clinical Trial of Quality- and Quantity-Cultured Peripheral Blood Mononuclear Cell Treatment for Androgenic Alopecia

research Uncontrolled Clinical Trial of Quality- and Quantity-cultured Peripheral Blood Mononuclear Cell Treatment for Androgenic Alopecia

October 2025 in “Plastic & Reconstructive Surgery”

This study evaluated the safety and effectiveness of MNC-QQ cell therapy in five men with androgenic alopecia, reporting no adverse effects and improvements in hair growth, hair density, and quality of life over six months.

research Novel Electrotrichogenic Device Promotes Hair Growth in Men With Androgenetic Alopecia: A Pilot Study

April 2025 in “Journal of Cosmetic Dermatology”

In this pilot study, the niostem device, a wearable device delivering low-level electrical stimulation, significantly increased hair density by 19.3% and thickness by 8.8% in male androgenetic alopecia patients over six months without reported adverse events.

Evaluation of the Safety and Efficacy of Concentrated Growth Factors for Hair Growth Promotion in Androgenetic Alopecia Patients: A Retrospective Single-Center, Single-Arm Study

research Evaluation of the safety and efficacy of concentrated growth factors for hair growth promotion in androgenetic alopecia patients: A retrospective single‐centre, single‐arm study

August 2024 in “Journal of Cosmetic Dermatology”

This study reported significant improvements in hair density and growth ratio in androgenetic alopecia patients receiving concentrated growth factor injections, with benefits sustained for 6 months.

Investigator-Blinded, Controlled, and Randomized Comparative Study on 1565 Nm Non-Ablative Fractional Laser Versus 5% Minoxidil for Treatment of Androgenetic Alopecia

research Investigator‐blinded, controlled, and randomized comparative study on 1565 nm non‐ablative fractional laser versus 5% minoxidil for treatment of androgenetic alopecia

January 2024 in “Journal of Cosmetic Dermatology”

This study reported that the 1565 nm non-ablative fractional laser treatment significantly improved various hair growth indices in patients with androgenetic alopecia compared to 5% minoxidil, demonstrating its superior clinical efficacy and safety for treating this condition.