The 1,927-nm Fractionated Thulium Laser Monotherapy Increases Hair Density in Patients with Male Pattern Hair Loss in Brazil: Prospective Clinical Study

December 2025 in “ Medical Lasers ”

Mariana Figueiroa Careta, Isabelle Wu, Luisa Reis Pinto, Luís Torezan

1,927-nm fractionated thulium laser male pattern hair loss prospective clinical study hair density terminal hair count thulium laser PHL

TLDR The laser treatment increased hair density in men with hair loss.

A prospective clinical study conducted in Brazil evaluated the efficacy and safety of a 1,927-nm fractionated thulium laser as a monotherapy for male pattern hair loss (PHL). The study involved 11 male patients who underwent 12 weekly laser treatment sessions. Results showed significant increases in total hair count (p = 0.021) and terminal hair count (p = 0.041), although no significant change was observed in average hair thickness per cm². The treatment was well tolerated, with only mild and transient redness reported. These findings suggest that fractionated thulium laser therapy could be a promising option for managing PHL, though further large-scale studies are needed to confirm its efficacy and long-term outcomes.

View this study on jkslms.or.kr →

Discuss this study in the Community →

Related Community Posts Join

6 / 1000+ results

community If you're sitting there wondering, "I'm losing my hair, what do I do?" then read my advice here. I've been fighting the fight for 7 years, with great success. (pictures included)

in Question 105 upvotes 12 years ago

Fighting hair loss with "The Big 3" treatments of Propecia, Rogaine and Nizoral shampoo, as well as specific advice on how to use these products. People have shared their long-term success stories and some have discussed the side effects of finasteride. Other suggestions included Lipogaine and Pura D'or Hair Loss Prevention Therapy Shampoo & Conditioner.

community 47, Used Finasteride and Minoxidil for 1 Year, No Results - Too Late to Regrow?

in General 84 upvotes 3 months ago

A 47-year-old used finasteride and minoxidil for a year without results and is concerned about whether it's too late to regrow hair. Another user suggests continuing the treatments and adding microneedling for potentially better results, emphasizing patience.

community Minoxidil + nizoral progress

in Journals / Progress Pictures 54 upvotes 3 months ago

The user shared progress pictures of their hair after using Minoxidil and recently adding finasteride to their daily treatment. They are seeking feedback on their progress.

community 30M Switching from 3-Year Topical Min/Fin to Oral Min – Seeking Advice

in General 80 upvotes 3 months ago

A 30-year-old is considering switching from a topical Minoxidil/Finasteride treatment to oral Minoxidil due to cost and insurance coverage. They seek advice on potential effects and experiences from others who have made a similar switch.

community 25M: Regrowth Chances After 5 Years on Minoxidil Alone Now Adding Finasteride and Others?

in General 64 upvotes 3 months ago

The user used minoxidil alone for 5 years and recently added finasteride, ketoconazole shampoo, bimatoprost, and dermarolling to their routine. They are hopeful for regrowth, as combining these treatments can address hair loss causes, but results may take up to a year.

community Question: Thickness Improvement from Finasteride to Dutasteride Switch?

in General 51 upvotes 3 months ago

Switching from finasteride and minoxidil to dutasteride and minoxidil can potentially lead to over 40% improvement in hair thickness in some cases, especially in young individuals who have plateaued after initial success. Generally, a 20% improvement is expected after six months.

Similar Research

6 / 1000+ results

research Laser Therapies in Androgenetic Alopecia: Review and Clinical Experiences

January 2025 in “Journal of Cutaneous and Aesthetic Surgery”

Low-level laser therapy effectively improves hair growth in androgenetic alopecia with minimal side effects.

research Therapeutic Efficacy and Safety of a 1927-nm Fractionated Thulium Laser on Pattern Hair Loss: An Evaluator-Blinded, Split-Scalp Study

21 citations , January 2018 in “Lasers in Medical Science”

The 1927-nm fractionated thulium laser treatment significantly improves hair thickness and count in pattern hair loss patients.

research Use of Fractionated Laser Therapy for the Treatment of Androgenetic Alopecia: A Systematic Review and Meta-Analysis

December 2023 in “Lasers in Medical Science”

Fractionated laser therapy, especially erbium-glass laser, effectively increases hair thickness in people with hair loss but doesn't increase the number of hairs.

research Laser and Light-Based Therapies in the Treatment of Hair Loss

1 citations , September 2019

Laser and light therapies can help regrow hair but need more research for best results.

research What Do We Know About Hair Growth Induced by Wounding and Its Therapeutic Applications?

August 2023 in “Dermatologic Surgery”

Wounding may stimulate hair growth, but more research is needed to confirm the safety and effectiveness of related treatments.

research Laser-Assisted Hair Regrowth

5 citations , April 2019 in “Plastic and reconstructive surgery. Global open”

Fractional lasers could help hair regrowth in androgenic alopecia, but more research is needed to confirm their effectiveness and safety.