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This review highlights the promising clinical outcomes of sacituzumab tirumotecan (sac-TMT), an antibody-drug conjugate for breast cancer that targets TROP2, demonstrating improved response rates and progression-free survival, with manageable safety concerns including primarily mild-to-moderate nausea and alopecia.

This literature review addresses generalized juvenile demodicosis in dogs, describing a case in a 10-month-old Dachshund where corticosteroid treatment worsened the condition, leading to severe pyoderma, intense itching, and widespread hair loss; it reports no new clinical findings.

This review discusses how increased gene copy number for telomerase components may contribute to telomerase up-regulation in cancer cells, although the exact mechanisms are not fully understood.

This article reviews the historical development and challenges of highway construction worldwide, highlighting key milestones from Italy's 1924 autobahn to China's leading pace in the 21st century, and reports no new results.

Most patients with Tuberous sclerosis had neurological or skin issues, and over half had psychiatric problems.

This study found that transcutaneous electrical acustimulation aided wound healing in mice by enhancing expression of proteins related to signaling pathways, stress recovery, and mitochondrial function.

This review discusses triboelectric nanogenerator (TENG) devices for body-integrated electrical stimulation therapy and suggests they may revolutionize personalized healthcare, but it reports no new clinical results.

Tissue-engineered skin substitutes can model junctional epidermolysis bullosa and may help develop gene therapy.

TEDAR is crucial for skin cell differentiation and barrier formation.

This article examines how digital technologies, drawing on Marshall McLuhan's concept of media as an "extension of man," transform design thinking by creating new possibilities without replacing it, emphasizing the need for a hybrid, reflective practice in design.

This study found that a single 2 ml injection of TEEV every 4 weeks offers similar beneficial effects with fewer side effects compared to injecting the same dose every 2 weeks in postmenopausal women.

This case report describes the first successful use of telitacicept in treating a patient with systemic lupus erythematosus and a history of papillary thyroid carcinoma, suggesting its potential as a therapeutic option for such conditions.

This article reviews the history of Portuguese and Spanish derivational suffixes and provides no new empirical findings, discussing various scholarly works and contributions on the subject.

This case series reported that telogen effluvium may reveal underlying traction alopecia, emphasizing the importance of recognizing this to ensure accurate diagnosis and treatment.

The authors concluded that capecitabine and high-dose toremifene may be an effective treatment option for patients unable to undergo anthracycline or taxane therapies, based on one woman's cancer management.

This study found that dihydrotestosterone induces hair loss in male C57BL/6 mice, and this effect can be partially reversed by the androgen receptor antagonist bicalutamide.

This study in Mexican adolescents with severe alopecia areata reported that oral tofacitinib treatment resulted in hair growth and reduced alopecia severity without serious adverse effects.

This study found that human placenta extract may be a promising pulp-capping material, causing less intense chronic inflammation and thicker dentine bridge formation compared to mineral trioxide aggregate in dogs' teeth.

In this study, researchers identified a specific T cell receptor associated with carbamazepine-induced severe cutaneous adverse reactions, demonstrating its potential for therapeutic development in patients with the HLA-B*15:02 genotype.

This article discusses the impact of PROTACs technology in transforming drug discovery with its novel degradation mechanism, but it reports no new experimental findings.

This review discusses the use of tofacitinib as a treatment for plaque psoriasis, highlighting its efficacy and safety in clinical trials, but notes unresolved questions regarding long-term safety.

In this study, the fixed oil extracted from Apeiba tibourbou seeds showed potential analgesic and anti-inflammatory properties, with prominent constituents including omega-3 and omega-6 fatty acids.

An intact skin barrier is crucial to prevent infection in cases of tether-induced tenosynovitis.

This study evaluated the resin oil of Copaifera officinalis L., identifying 64 compounds and developing validated analytical methods for quality control, and formulated a stable pharmaceutical foam, laying groundwork for potential clinical applications of copaiba oil.

This study found that topical tacalcitol improved roughness and scaling in erythromelanosis follicularis faciei et colli, although it was less effective for facial erythema.

Direct-to-consumer teledermatology is not effectively reaching underserved populations due to language, technology, and insurance barriers.

This study found that high doses of TCB caused severe toxicity in cotton top marmoset monkeys, with clinical and histological changes similar to those in humans and other primates exposed to PCBs.