18 citations
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July 2016 in “Medicine” This study suggests that crosstalk between Wnt/β-catenin and TGF-β signaling pathways may contribute to the development of androgenetic alopecia.
18 citations
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March 2020 in “Frontiers in Neuroendocrinology” This study suggests that synthetic steroid analogues or 5α-reductase modulation could be potential therapeutic strategies for nervous system disorders, but further research on their effects is necessary.
16 citations
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February 2018 in “BMC Genomics” This paper reviews genome-based personalized medicine developments using Web services for analyzing SNPs in reproductive potential but reports no new clinical findings.
16 citations
,
March 2017 in “Bone Marrow Transplantation” In this study, permanent alopecia after haematopoietic stem cell transplantation was found in 16% of patients and was significantly associated with conditioning regimens involving busulphan.
15 citations
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January 1992 in “Sen'i Gakkaishi” This study suggests that the cell membrane complex in hair cuticles contains hydrophilic regions with disulfide bonds allowing polymer uptake and hydrophobic lamella-like lipid layers.
10 citations
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November 2012 in “International Journal of Dermatology” This study identified that certain diseases, including AIDS and systemic lupus erythematosus, may cause African hair to change to a silky, wavy texture similar to neonatal hair in affected patients.
9 citations
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March 2022 in “Antioxidants” This review summarized and classified 32 approved synthetic and natural-identical antioxidants, examining their regulatory status, safety, pharmacological properties, and effectiveness on human health, aiming to clarify their antioxidant actions and encourage further research in the field.
9 citations
,
December 2021 in “Androgens” This review explores how androgen administration might help alleviate inflammation and mitochondrial impairment in traumatic brain injury but reports no new experimental findings, calling attention to the need for further investigation.
8 citations
,
July 2010 in “Aesthetic Plastic Surgery” The study concluded that increasing the GSH concentrations in preservation solutions for follicular units doesn't lessen the oxidative stress during cold ischemia and reperfusion in hair transplantation surgery.
7 citations
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March 2012 in “Journal of Investigative Dermatology” This study presents evidence that specific thymus-derived peptides affect human hair follicle growth, identifying thymulin as a potential hair growth stimulator despite interindividual response variations.
5 citations
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September 2015 in “Journal of The American Academy of Dermatology” This letter highlights that the effectiveness of skin self-photography for melanoma detection has not been evaluated, although it could be a cost-effective option for patients without access to professional skin photography.
4 citations
,
October 2000 in “Contraception” This study found that a regimen combining cyproterone acetate and testosterone buciclate induced reversible azoospermia in bonnet monkeys, highlighting its potential as an effective male contraceptive.
4 citations
,
November 2022 in “Acta dermato-venereologica” This study found that patients with hidradenitis suppurativa had lower trabecular bone score and total hip bone mineral density compared to controls, with a high prevalence of vitamin D deficiency.
2 citations
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January 2025 in “Сибирский научный медицинский журнал” In this study using a mouse model, the authors reported that the synthetic antioxidant TS-13 effectively inhibited tumor growth comparably to doxorubicin and reduced chemotherapy side effects, such as weight loss, splenotoxicity, and alopecia, more effectively when combined with the cytostatic treatment.
2 citations
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January 2011 in “Andrologia” This study concluded that 16β-methyl-17α-benzoyloxypregnen-4-en-3,20-dione may be a promising treatment for androgen-dependent diseases and epilepsy due to its antioxidant effects and impact on GABAergic and serotonergic metabolism in rats.
1 citations
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September 2011 in “UHOD : Uluslararası hematoloji - onkoloji dergisi” This study found no significant differences in age, sex, or histopathological characteristics for differentiating basal cell carcinoma from benign tumors of cutaneous appendages, complicating diagnosis.
1 citations
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September 2019 in “Journal of surgery and medicine” This study found that women with polycystic ovary syndrome had worse meibomian gland morphology and ocular surface conditions compared to healthy controls, as observed through non-contact meibography.
May 2023 in “Sokoto journal of medical laboratory science” This study demonstrated that prolonged use of commercial hair dyes caused significant increases in liver enzymes and bilirubin levels, and evident cellular injury in the skin and liver tissues of Albino rats, indicating potential toxicity.
This study found that theabrownin-selenium nanoparticles (TB-Se NPs) effectively target Malassezia-induced dermatitis through a dual antifungal and immunomodulatory mechanism, suppressing fungal overgrowth, reducing inflammation, and enhancing immune memory to prevent recurrence in a dermatitis model.
February 2025 in “Revista Eletrônica Acervo Saúde” This report emphasizes the importance of considering thyroid tuberculosis in the differential diagnosis of cervical masses, highlighting the role of biopsy and histopathological examination for accurate diagnosis and treatment.
April 2018 in “Journal of Investigative Dermatology” This study found that patients taking hydroxychloroquine had a significantly higher likelihood of indeterminate QuantiFERON-TB Gold test results compared to those not on the medication, independent of other immunosuppressive drug use.
November 2024 in “Forensic Sciences” This review highlights the potential for using the Y chromosome in epigenetic analyses to better understand male-specific aging and disease mechanisms.
September 2024 in “Journal of Ethnopharmacology” In this study, Terminalia bellirica extracts promoted hair regrowth in testosterone-induced AGA mice, possibly by inhibiting type II 5α-reductase activity and enhancing the MAPK signaling pathway.
October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study demonstrated that disrupting EGFR signaling in mice leads to immune sensitivity compromising the hair follicle's protective environment, but JAK1/2 inhibition can restore this immune privilege and stimulate hair growth, suggesting a potential therapy for scarring hair loss diseases like cicatricial alopecia.
July 2023 in “International Journal of Molecular Sciences” In this study, Trapa bispinosa Roxb. pericarp extract demonstrated inhibitory effects on 5α-reductase activity both in vitro using LNCaP cells and in vivo in a mouse model of benign prostatic hyperplasia, suggesting its potential role in managing the condition.
July 2023 in “Journal of Microbiology and Biotechnology” This study found that oral administration of Terminalia bellirica enhanced hair growth in testosterone-suppressed conditions in both human cell and mouse models, outperforming finasteride, a current commercial hair loss treatment.
May 2023 in “The Journal of Immunology” In this study of C3H/HeJ mice, researchers observed that alopecia areata is associated with the expansion of exhausted-memory CD8 T cells in multiple organs, with autoreactive activation not fully explained by known mechanisms, shedding light on the immunological dynamics underlying the condition.
August 2019 in “Journal of Invertebrate Pathology” This study observed that different alkaline buffers had a significant impact on the volume of liquid consumed by fall armyworm larvae, emphasizing the importance of measuring imbibed volumes to reduce dose errors in bioassays.
January 2012 in “Zhongguo linchuang xinlixue zazhi” This study found that oxidative stress from chronic restraint stress delayed the anagen phase in the hair cycle of mice, but antioxidant treatment partially reversed this effect.
December 2007 in “Röntgenpraxis” This review discusses various treatments for androgenic alopecia, highlighting FDA-approved options and other commonly used therapies, but reports no new clinical results.