Some Histological and Biochemical Evaluation on Commercial Hair Dyes

The study "Some histological and biochemical evaluation on commercial hair dyes" conducted by Stanley Obialor Anyanwu, Agala Egbe, and Iwaeni Bassey Eborty-Ike, aimed to assess the toxicity of different commercial hair dyes on the skin and liver of Albino rats. The study, conducted between May and October 2019, involved 20 male Albino rats, divided into five groups of four. Four different hair dye colors were applied topically on the rats for 30 days, after which the rats were sacrificed for histological and biochemical analysis. The results showed that the serum levels of Alkaline phosphatase (ALP), Aspartate Amino transferase (AST), Total protein (TP), Total bilirubin (TB), and conjugated bilirubin (CB) in all the test groups were significantly increased compared to the control group (P=0.001). Histological evaluations indicated evidence of cellular injury in all the test groups. The study concluded that prolonged use of commercial hair dyes caused adverse effects to the skin and liver.