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In this narrative review, the authors found that stigma related to oculocutaneous albinism in Africa is primarily driven by socio-cultural beliefs and structural inequities, affecting individuals' health, education, and psychosocial well-being, with interventions needed to dispel myths and provide specialized healthcare and support.

This review discusses mammalian models of epimorphic regeneration to define a vertebrate regeneration blastema, concluding that regenerative failure likely stems from cellular responses to the microenvironment after injury, not progenitor cell availability, and calls for targeted modification studies in mammals to advance human regeneration.

This study suggests that dermal adipocytes might play a key role in skin aging due to their transformation into fibrotic structures in chronically photo-damaged skin.

This study found that chitosan microparticles containing minoxidil sulphate sustained its release and may hold potential for targeted topical treatment of alopecia.

This study found that in Arabidopsis seedlings, tonoplast intrinsic proteins are targeted to the vacuole via at least two pathways, including pathways with differing sensitivity to a chemical inhibitor that affect root hair growth and PIN2 targeting.

This study found that the sebum partition coefficient (K(sebum)) for some drugs differs from the stratum corneum partition coefficient (K(sc)), indicating its importance for targeted drug delivery into hair and sebaceous follicles.

The authors concluded that dermal white adipose tissue, influenced by factors like light irradiation, plays a significant role in modulating hair follicle cycles and could be targeted for hair growth treatments.

In this study, melatonin administration enhanced various cellular and structural features of the scrotal skin in Soay rams, including increased thickness, cell count, and gland activity.

This study demonstrates that Rac1 activity is essential for normal hair follicle formation but influences hair structure and pigmentation, in terminal differentiation, through alterations in hair shaft, cuticle, and pigmentation organization.

This study introduced a novel nonsteroidal androgen receptor antagonist that effectively controls sebum production in the golden Syrian hamster ear model through targeted follicular delivery.

This article discusses how challenges in drug development and success rates are driving a shift in the pharmaceutical industry towards engineering targeted drug delivery systems, with nanomaterials offering potential solutions for selective therapeutic delivery.

This review discusses lipid-polymer hybrid nanoparticles for dermatological applications, outlining their structural and formulation advancements, but reports no new clinical results and calls for further research on their therapeutic potential.

This study found that by using an automated system to analyze skin histology, 108 structural features were significantly affected by age, and it identified four new aging biomarkers and notable sex-based differences in skin aging.

This overview examines the biology, origin, structure, and function of various cells and structures, such as the blood-retinal barrier and Merkel cells, and discusses their roles in disease pathogenesis, along with recent findings related to the lymph nodes' paracortex.

This review found that 3D bioprinting significantly advances skin tissue engineering by enabling the creation of complex, patient-specific skin structures, though technological and regulatory challenges persist, particularly in areas like scalability and physiological mimicry.

This review highlights recent advancements in the engineering of skin organoids using hydrogels, which improve their structural and functional fidelity by supporting the architecture and integration of vascular and neural components, promising to enhance regenerative medicine, drug discovery, and complex skin disorder studies.

This review synthesizes evidence that photobiomodulation may provide robust symptomatic relief for knee osteoarthritis but indicates its potential for structural regeneration remains speculative and needs further long-term validation.

This review highlights that two-photon excitation microscopy is a valuable tool for visualizing live skin structures and immune responses at high resolution, though its clinical use is hindered by safety and cost issues.

This study found that exosomes derived from human amniotic mesenchymal stem cells enhanced stem cell proliferation and structural restoration in irradiated salivary glands of rats, with significant improvements observed by day 7, suggesting activation of the Wnt signaling pathway.

In this study, the derivation of certain topological indices was used to represent the molecular structure of drugs for alopecia treatment, like Minoxidil and Finasteride, which may support medication investigations, especially in resource-limited settings.

This study used molecular docking to identify stiripentol as a potential new inhibitor of the SRD5A2 enzyme, which is targeted for treating androgen-related diseases; however, in vivo trials are needed to validate its efficacy.

This study developed finite element models to examine skin's biomechanical properties, finding that structural heterogeneities like Rete ridges and hair follicles create distinct stress and strain patterns that may influence mechanosensation and skin integrity.

This review highlights the potential of microneedle devices in dermatology for conditions like skin aging and autoimmune skin diseases, emphasizing their ability to facilitate targeted drug delivery by creating temporary skin pathways.

This study reports that transplantation and in vivo reprogramming using specific reprogrammed cell types can generate skin appendage-like structures in adult mice, suggesting potential therapeutic avenues for skin regeneration and disorders.

This article reviews treatment options for androgenetic alopecia and suggests that therapy should be personalized and targeted at various pathophysiological aspects, but reports no new clinical findings.

This study found that in a mouse model, alopecia areata was associated with changes in heart structure, biochemistry, and gene expression linked to cardiac hypertrophy after ACTH exposure.

This review summarizes recent advances in nanomedicine-based therapies for psoriasis, highlighting their potential to provide targeted and sustained therapeutic effects by modulating key cellular components and signaling pathways involved in the disease, offering novel perspectives for future treatment development.

This review highlights that bicalutamide, a non-steroidal antiandrogen used in prostate cancer treatment, is mainly effective through its (R)-enantiomer and emphasizes the need to monitor its adverse effects despite its targeted antiandrogenic action.

This study found that integrating Lactobacillus-rich probiotic nutrition and fractional CO₂ laser therapy with clotrimazole in mucoadhesive hydrogels significantly improved clinical and structural outcomes for women with recurrent vulvovaginal candidiasis, suggesting a promising advanced therapy, though further validation in larger trials is needed.

This review discusses the role of reactive oxygen species in wound healing, highlighting potential strategies like mitochondrial-targeted antioxidants for managing non-healing chronic wounds, and reports no new clinical results.