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The document says that hirsutism in women usually needs hair removal and hormone treatment to manage symptoms and improve well-being.

AIRE protein, defective in APECED patients, is found in skin and hair cells and interacts with cytokeratin 17.

Hair thinning causes stem cell loss through a process involving Piezo1, calcium, and TNF-α.

Hedgehog pathway inhibitors can treat certain aggressive cancers but face limitations like resistance and side effects.

Citrullinated proteins from Porphyromonas gingivalis may contribute to rheumatoid arthritis.

Mutations in NIPAL4 cause skin issues by disrupting lipid layers, but some improvement is seen with topical treatment.

Alkaline Ceramidase 1 prevents early hair loss in mice by keeping hair follicle stem cells balanced.

Older men with low levels of a testosterone byproduct had a higher chance of developing an irregular heartbeat.

The method accurately measures hormones and endocannabinoids in mice, showing gut microbiota diversity affects these levels and may influence stress and reproductive systems.

A specific gene variant causes severe skin issues and increases infection risk, requiring careful medical monitoring.

The document concludes that a systematic approach is crucial to identify causes of androgen excess in women beyond the most common cause, Polycystic ovary syndrome (PCOS).

Activating Nrf2 in skin cells speeds up wound healing by increasing the growth of certain stem cells.

Taking tadalafil and finasteride together is safe and effective for treating urinary symptoms and erectile dysfunction in men with enlarged prostates.

Identical twins had different symptoms because one had more cells with an extra chromosome fragment in different tissues.

A new mouse mutation causes skin and hair defects due to a gene change.

A new mutation in the ST14 gene broadens the understanding of ichthyosis-hypotrichosis syndrome.

Testosterone therapy may slightly increase sexual desire in women with HSDD but lacks broad recommendation due to safety concerns and limited approval.

Sorafenib often causes mucositis, hand-foot syndrome, rash, alopecia, diarrhea, and fatigue.

Prostate cancer can progress even with low testosterone due to internal hormone production in the tumor.

Girls with PCOS have higher levels of certain androgens, which are linked to excess hair growth, but these androgens don't help diagnose PCOS.

Taking triterpenoids from Ganoderma lucidum over a long time can help slow down brain aging and improve overall health in mice.

Frontal fibrosing alopecia is a poorly understood condition with increasing cases and unclear treatment effectiveness.

Mice without the enzyme HSD17B3 still produce normal testosterone, suggesting they have different ways to make it compared to humans.

Omega-6 fats in certain cells boost male hormone production.

The method can measure multiple steroids in human hair to study long-term steroid metabolism, especially in newborns and children.

The new hair graft device is faster, more efficient, and reduces damage to hair follicles.

RF energy is used in medical and beauty treatments to heat tissues, tighten skin, and reduce fat safely.

Taking Dutasteride with Ketoconazole can increase Dutasteride's effects and side effects.

Genomic research can help improve the quality and production of natural fibers in animals.

Wnt/β-catenin signaling is important for keeping skin cell attachment structures stable.