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Memory T cells in the skin balance staying put and moving into the blood, clustering around hair follicles, and increasing in number after infection.

Minoxidil treats hair loss, promotes growth, has side effects, and has recent patents.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

Bioprinting could improve wound healing but needs more development to match real skin.

Peptide hydrogels heal burn wounds faster and better than standard dressings.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

The document concludes that accurate diagnosis of ichthyosis is crucial for treatment and genetic advice, and ongoing research is needed for better therapies.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.

Aging causes skin stem cells to work less effectively.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

The document concludes that a better understanding of cell changes during wound healing could improve treatments for chronic wounds and other conditions.

Keratose, derived from human hair, is a non-toxic biomaterial good for tissue regeneration and integrates well with body tissues.

Liposomes improve drug delivery and reduce skin irritation in dermatology.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

Transplant success has improved with better immunosuppressive drugs and donor matching.

Androgenetic alopecia in women needs more research and better management strategies.

K6hf is a unique protein found only in a specific layer of hair follicles.

Understanding hair follicle anatomy helps diagnose hair disorders.

Masculine facial features may not reliably indicate heritable health, and more research is needed.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Facial feminization surgery is effective in helping transgender women appear more feminine and has high patient satisfaction.

Adam10 enzyme is crucial for healthy skin and proper Notch signaling.

Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.

Macrophages help heal nerves by aiding the maturation of Schwann cells and are important for nerve repair.

Mouse hair follicle cells briefly grow during the early hair growth phase, showing that these cells are important for starting the hair cycle.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.

Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.