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Skin stem cells are crucial for maintaining and repairing the skin and hair, using a complex mix of signals to do so.

Removing the ATR gene in adult mice causes rapid aging and stem cell loss.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.

Turning white fat into brown-like fat could help fight obesity and type 2 diabetes.

Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.

Hair growth phase and certain genes can speed up wound healing, while an inflammatory mediator can slow down new hair growth after a wound. Understanding these factors can improve tissue regeneration during wound healing.

Basal cell carcinoma mostly starts from cells in the upper skin layers, not hair follicle stem cells.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.

Increasing mir-302 turns human hair cells into stem cells by changing gene regulation and demethylation.

Stem cell-derived conditioned medium shows promise for treating various medical conditions but requires standardized production and further validation.

Stromal stem cells may help heal wounds by becoming structural cells or affecting the immune system, but more research is needed to understand how.

The circadian clock affects skin stem cell behavior, impacting aging and cancer risk.

The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.

The research shows that a gene called Wnt3 affects hair growth and structure, causing short hair and balding when overactive.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.

Wnt1/βcatenin signaling is crucial for heart repair after injury.

Fat cells help recruit healing cells and build skin structure during wound healing.

The timing of when the gene Bmal1 is active affects aging and survival, with its absence during development, not adulthood, leading to premature aging.

Hair growth and pigmentation in mice involve specific stages crucial for research.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

Understanding where cancer cells come from helps create better prevention and treatment methods.

Diet changes can protect against harmful environmental effects on fetal development.

Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.

Tiny pollution particles called PM2.5 can harm skin cells by causing stress, damage to cell parts, and cell death.

Planarian regeneration begins with a specific gene activation caused by injury, essential for healing and tissue regrowth.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.