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This study observed that a 3D culture model of hair follicle cells showed an anagen-like phase between days 3 to 6 and transitioned to a catagen-like phase by day 7, highlighting cell differentiation and structural development over time.

A 45-year-old woman with autoimmune diseases experienced patchy hair loss due to alopecia areata, which has no cure but can be treated, with varying success.

Proximal hair cortisol is a reliable tool for diagnosing Cushing's Syndrome.

In this study, researchers found that alopecia areata is linked to immune cell activation against hair follicle autoantigens and is associated with heart changes and cardiac marker alterations in humans and mice.

This case report details a 7-year-old Shih Tzu with pituitary-dependent hyperadrenocorticism, where initial trilostane treatment did not improve skin conditions, necessitating a dosage increase.

People with hair loss have low zinc levels; zinc supplements and laser therapy may help.

This study found that androgenic steroids, particularly androstenedione and androstanedione, significantly reduced the growth of certain dermatophytes, suggesting hormonal influence on fungal infections in hair follicles.

In this pilot study, finasteride increased testosterone/dihydrotestosterone and progesterone/dihydroprogesterone ratios in normal ovulatory women but did not alter ovulation or gonadotropin secretion.

This study observed that long-term recombinant interferon alpha-2b therapy was associated with considerable hair loss in some patients, indicated by a telogen effluvium pattern on trichograms.

This review discusses how recent studies use models and experiments to understand immune system signaling, but it reports no new clinical findings; the authors suggest strategies for improving these models.

In this study, gamma/delta T cells were observed in skin after allergic or irritant reactions to heavy metal salts, suggesting a role in skin defense against these metals.

In this study of healthy men, low levels of testosterone and dihydrotestosterone were associated with higher body mass index, fat content, and insulin resistance, but their effects on lipid and glucose metabolism were similar in quality.

This study presents a rare case of alopecia totalis occurring after the use of permanent hair dye.

This letter to the editor reports a case of alopecia universalis occurring alongside minimal change nephrotic syndrome, but it presents no new clinical findings.

Immune cells called Treg cells are essential for hair growth and regeneration.

In this study of male patients with 46,XY 5α-reductase type 2 deficiency, DHT therapy was effective in achieving penile enlargement during infancy, while testosterone replacement therapy proved more beneficial during puberty, possibly due to increased conversion to DHT.

New hair regrowth model proposed, imiquimod found to kill skin cancer cells, T-cadherin loss linked to invasive skin cancer, no clear gene link to skin cancer after transplant, and study on children's hair loss shows male dominance and genetic ties.

Targeting TCR-Vβ2 in cutaneous T cell lymphoma shows promise for safer, more specific treatment.

This study found that patients with systemic lupus erythematosus and diffuse hair loss showed non-scarring alopecia without inflammation and a decrease in total hair follicles.

This study found that delivering math1 via an adenovector led to vestibular hair cell regeneration and improved balance function in ototoxin-treated adult mice.

This study found that activation of Wnt/β-catenin signaling in mouse testes promotes spermatogonial differentiation and reduces the stem cell pool, with SHISA6 inhibiting this process and maintaining stem cell characteristics.

This study found that testosterone and 5α-dihydrotestosterone induced apoptosis in dermal papilla cells from nonbalding scalp regions, suggesting a high androgen stimulus can trigger cell death related to androgenetic alopecia.

This study found that while ethinyl oestradiol and cyproterone acetate effectively treated hirsutism in 90% of patients, 80% experienced relapse within six months after stopping treatment, suggesting long-term use is necessary.

This study suggests that in gilthead seabream, DHT is involved in the onset of the meiotic phase of spermatogenesis and influences serum levels of E2 through regulation of aromatase activity.

In this study using the C3H/HeJ mouse model of alopecia areata, researchers found that hyperexpanded CD8⁺ T cell clones were sufficient to initiate disease, establishing a causal link between T cell clonality and pathogenicity.

This study found that patients with androgenetic alopecia experienced more severe symptoms than those with alopecia areata, influencing their quality of life differently based on various patient characteristics.

In this study, oral Bhringaraj extract was found to significantly reduce hair shedding in adults over 24 weeks, according to comb test measurements and patient-reported improvements, with mild and self-resolving side effects observed.

The study introduced an advanced skin model, ImmuSkin-MT, which effectively distinguished between different strengths of skin sensitizers by mimicking the interaction of immune cells in skin tissue.

In this study, oral minoxidil treatment significantly increased serum VEGF levels and improved hair growth measures compared to a control group, suggesting its potential as an effective approach for promoting hair regrowth in androgenetic alopecia.