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Two patients treated with TAC for mouth fibrosis improved but developed Cushing's Syndrome symptoms.

Personalized treatments for hair loss are becoming more effective by using genetic information.

Imiquimod can cause rare skin side effects, some irreversible, and long-term follow-up is important for users.

The study found that tight junctions reach the top layer of the skin's stratum granulosum, not just the second top layer as previously thought.

Frog skin cells need the protein desmoplakin for proper development and cell layer formation.

Thyroid disease can cause hair loss and treating thyroid problems might help with hair disorders.

The effects of estrogen on human hair growth are unclear and need more research.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

Natural molecules like inositols, resveratrol, vitamins, and omega-3 fatty acids may help manage Polycystic Ovary Syndrome (PCOS), but their effects vary and need more exploration.

Low-dose oral minoxidil effectively treats non-scarring hair loss with some side effects like hypertrichosis and postural hypotension.

Effective treatments for excessive hair growth in women include creams, laser therapy, and medications, with the choice depending on individual needs and potential side effects.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Liposomes improve drug delivery and reduce skin irritation in dermatology.

Genetics and hormones play a role in male and female hair loss, but more research is needed to fully understand it.

Male pattern baldness may be caused by scalp pressure on hair follicles, which increases with age and leads to a cycle of hair loss. This process is not directly determined by genes.

Hair from balding and non-balding areas regrows similarly on mice.

Setipiprant may reduce inflammation by blocking an enzyme called aldose reductase.

Finasteride may affect PNMT, causing side effects.

5-alpha reductase inhibitors can cause sexual, neurologic, endocrine, and cardiovascular side effects, but these are rare and usually stop after ending treatment.

Hormonal treatments can help with hair loss, acne, and excess hair growth, but it takes 3-6 months to see results and patients should know the possible side effects.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Mice hair growth patterns get more complex with age and can change with events like pregnancy or injury.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

Nanoparticulate systems improve drug delivery by controlling release, protecting drugs, changing absorption and distribution, and concentrating drugs in targeted areas.

Diagnose and manage CCCA with thorough history, exams, and labs; treat with anti-inflammatory agents, stress reduction, and stopping harmful hair practices.

Oral zinc sulphate reduces dark hair color in mice.

New method measures female hair loss: Female Pattern Hair Loss Severity Index (FPHL-SI).

Finasteride for hair loss increases risk of long-lasting sexual dysfunction.

Inhaled steroids in children may cause excessive hair growth and not always go away after stopping the medication.

Obstetrician/gynecologists can diagnose and manage female hair loss with careful history taking and examination.