research Immunological and Metabolic Causes of Infertility in Polycystic Ovary Syndrome
PCOS causes infertility mainly due to hormonal imbalances, insulin resistance, and chronic inflammation.
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research Diabetes Mellitus Inhibits Hair Follicle Regeneration by Inducing Macrophage Reprogramming-Mediated Pyroptosis
Type 1 Diabetes prevents hair growth by causing cell death in hair follicles.
research Cell Death in Skin Function, Inflammation, and Disease
Different types of cell death affect skin health and inflammation, and understanding them could improve treatments for skin diseases.
research Neuroendocrine Perspectives in Alopecia Areata: Does Stress Play a Role?
Stress might contribute to hair loss in alopecia areata.
research Skin Microbiome, Metabolome and Skin Phenome, from the Perspectives of Skin as an Ecosystem
Your skin is like an ecosystem, with its own community of microbes and substances that interact and affect its health.
research Proteomics as a Tool to Improve Novel Insights into Skin Diseases: What We Know and Where We Should Be Going
Proteomics combined with other technologies can lead to a better understanding of skin diseases.
research Advances in Chitosan-Based Nanoparticles for Drug Delivery
Chitosan, a natural substance, can be used to create tiny particles that effectively deliver various types of drugs, but more work is needed to improve stability and control of drug release.
research Heat-Killed Lacticaseibacillus Paracasei GMNL-653 Ameliorates Human Scalp Health by Regulating Scalp Microbiome
Shampoo with heat-killed Lacticaseibacillus paracasei GMNL-653 improves scalp health and hair growth by changing scalp bacteria.
research Long-Acting Microneedle Formulations
Microneedles are promising for long-acting drug delivery and can improve patient compliance, but more data is needed to confirm their effectiveness.
research An Innovative Phase 1b Trial Demonstrating Proof-of-Pharmacology for Two Novel IRAK4-Inhibitors Using a Local and Systemic Driven Immune Response
Two new IRAK4-inhibitors effectively reduced skin inflammation and immune response markers in healthy volunteers.
research Three Cases of Immune-Mediated Adnexal Skin Disease Treated with Cyclosporin
Cyclosporin effectively and safely treated skin diseases in three pets with no side effects.
research Corticotropin-Releasing Hormone and the Skin
CRH in the skin acts like the body's stress response system, affecting cell behavior and immune activity.
research Skin Diseases Associated With Atopic Dermatitis
People with atopic dermatitis are more likely to develop other skin conditions due to shared genetics and immune pathways.
research The Role of Leptin in Selected Skin Diseases
Leptin affects skin and hair health and may worsen some skin conditions, but more research is needed to understand its full impact.
research Microneedle Arrays Combined With Nanomedicine Approaches for Transdermal Delivery of Therapeutics
Microneedle arrays with nanotechnology show promise for painless drug delivery through the skin but need more research on safety and effectiveness.
research The Probable Destructive Mechanisms Behind COVID-19 on Male Reproductive System and Fertility
COVID-19 may harm male fertility and damage the reproductive system.
research An Integrated Model of Alopecia Areata Biomarkers Highlights Both Th1/Th2 Upregulation, with Stronger Correlations Between Th2 Activation and Disease Severity
Both Th1 and Th2 immune responses are increased in alopecia areata, with Th2 response more strongly linked to how severe the disease is.
research Dermal White Adipose Tissue: A Newly Recognized Layer of Skin Innate Defense
Skin fat plays a key role in immune defense and healing beyond just storing energy.
research Microneedles as the Technique of Drug Delivery Enhancement in Diverse Organs and Tissues
Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.
research Microneedle Transdermal Drug Delivery Systems for Allergen-Specific Immunotherapy, Skin Disease Treatment, and Vaccine Development
Microneedles are a promising method for drug delivery, offering efficient and convenient alternatives with fewer side effects.
research Probiotic Bacteria Induce a Glow of Health
Probiotic bacteria improved skin and hair health in aged mice.
research Management of Autoimmune-Associated Alopecia Areata
Treatments for autoimmune hair loss have limited success and often relapse, and emotional support is crucial for those affected.
research Management of Primary Cicatricial Alopecias: Options for Treatment
There are many treatments for permanent hair loss disorders, but their effectiveness varies and there's no clear best option.
research Ethosome as a Potential Transdermal Drug Delivery System
Ethosomes are a promising way to deliver drugs through the skin.
research Cicatricial Alopecias: Diagnosis and Treatment Complexities
The document concludes that more research is needed to better understand and treat scarring hair loss conditions.
research COVID-19 and Endocrine and Metabolic Diseases: An Updated Statement from the European Society of Endocrinology
People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.
research The Novel Mechanisms and Applications of Exosomes in Dermatology and Cutaneous Medical Aesthetics
Exosomes can improve skin health and offer new treatments for skin repair and rejuvenation.
research Protoporphyrin IX: The Good, the Bad, and the Ugly
Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.
research Therapeutic Strategies for Treating Hair Loss
The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.
research Liposomes with an Ethanol Fraction as an Application for Drug Delivery
Ethosomes improve drug delivery through the skin but may have side effects like irritation.