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MK-0773 safely increased muscle mass but did not improve muscle strength or function in elderly women with sarcopenia.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

PrEP for HIV is less effective in transgender women mainly due to low adherence to the treatment.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Early diagnosis and treatment, using finasteride, minoxidil, or hair transplantation, improves hair loss outcomes.

Lecithin organogels could be good for applying drugs to the skin because they are stable, safe, and can improve drug absorption.

A gene called APCDD1, which controls hair growth, is found to be faulty in a type of hair loss called hereditary hypotrichosis simplex.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

The ZIP7 gene helps control zinc levels in cells by moving zinc from the Golgi apparatus to the cytoplasm.

Fungi-produced compounds can change plant root growth.

Androgens may cause hair loss by increasing TGF-beta1 from scalp cells, which inhibits hair cell growth.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.

Researchers created human hair follicles using a new method that could help treat hair loss.

Sulforaphane from broccoli can help protect skin from sun damage.

Essential oils in cosmetics can offer benefits but may cause allergies and should be used carefully.

Opioid painkillers can cause many side effects, including breathing problems and addiction, but are generally considered safe when used properly.

Some treatments can help with a hair loss condition called alopecia areata, but none ensure lasting results; choices depend on the person, with JAK inhibitors showing promise for severe cases.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Special fiber materials boost the healing properties of certain stem cells.

Androgens can help prevent memory problems caused by apoE4.

Hair loss in men is common, treatable, but not curable.

Erectile dysfunction is increasingly common in men under 40, with many physical and psychological causes, and various treatment options available.

Isotretinoin is highly effective in treating severe acne, rosacea, and gram-negative folliculitis.

Capsaicin, found in chili peppers, can slow down hair growth by affecting skin cells and hair follicles.

Hair loss needs more research for better treatments.

Oestrogens are key for bone growth during puberty in both boys and girls.

Lower doses of treatments for hirsutism and acne in PCOS are effective and cause fewer side effects.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.