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Covers common skin issues in kids, their diagnosis, treatment, and need for specialist care.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Good nutrition is crucial for health and preventing disease, and supplements can help prevent nutrient deficiencies.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Testosterone replacement may help post-menopausal women with androgen insufficiency, but more research is needed on its benefits and risks.

Treating excessive hair in women requires a holistic approach, including medical, aesthetic, and emotional support.

Activating TLR5 in the gut can extend lifespan and improve health in aged mice.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Hormonal therapy is a treatment option for acne, the only medical treatment for hirsutism, and the most promising for androgenetic alopecia.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Women with PCOS are more likely to suffer from depression, anxiety, and stress.

The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.

Eating a balanced diet with the right vitamins and minerals is important for healthy hair, but too many supplements can be harmful.

NF-κB signaling is crucial in many diseases and can be targeted for new treatments.

Men with male pattern baldness are more likely to have unhealthy blood lipid levels, which could signal other health issues.

Shift work disrupts the body's natural clock, leading to health problems.

Baricitinib and its combination with lonafarnib improve fat cell formation in certain genetic disorders.

Central lipohypertrophy in HIV-infected women may lead to shorter eyelashes.

The conclusion is that obesity should be managed with a slow, balanced approach to diet and exercise, with medication and surgery as additional options, and education and access to care are important.

Myotonic Dystrophy may age cells faster, and drugs that target aging could be potential treatments.

The Rotterdam Study aims to understand various diseases in older adults.

Women with PCOS are more vulnerable to severe COVID-19 and related health issues.

Balding and low testosterone increase risk of urinary stones.

Skin symptoms can indicate endocrine disorders and have various treatments.

Certain skin conditions can indicate insulin resistance and should prompt lifestyle changes and medical treatment to manage underlying health issues.

Metformin improved insulin resistance and BMI in overweight Taiwanese women with PCOS, and a 2-hour insulin test may be a good screening tool.

Patients with acanthosis nigricans often have insulin resistance and signs of increased male hormones, but treatment targeting these male hormones is generally ineffective.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.