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This study developed a foxn1-deficient Xenopus laevis model using CRISPR/Cas9, observing reduced T-cell markers and altered immune responses in tadpoles, providing a nonmammalian model for immunological research.

This study found that the proteins Par3, mInsc, and Gαi3 cooperate to regulate LGN polarization and promote perpendicular cell divisions during murine epidermal morphogenesis.

In this study, researchers developed a relatively simple punch assay for regenerating hair follicles using mouse or human cells, finding efficient hair formation with mouse cells but low efficiency with human cells on reconstituted human skin.

This study developed a method to convert fibroblasts into sweat gland-like cells, suggesting potential for regenerating damaged skin and restoring sweat gland function.

This study found that disruptions in planar cell polarity signaling are implicated in congenital heart defects and cardiomyopathy in developing mouse hearts, associated with early cardiomyocyte disorganization and improper heart looping.

This review discusses three aspects of cell fate specification across Metazoa and reports no new experimental results, highlighting the formation of nematode equivalence groups, evolution of echinoderm skeletogenic mesoderm, and adult cell fate regulation.

Sox13 is a new marker for early hair follicle development and differentiation.

Mouse embryos can develop in chick embryos, but they grow smaller with some organ issues.

Human hair follicles can grow back.

In this study involving a mouse model, researchers reported that intranasal delivery of protein-based CRISPR/dCas9 nanoparticles targeting the gene *Sirt1* reduced cerebral edema and increased survival following ischemic stroke, with no significant toxicity observed.

This study found that tyramine-linked hyaluronan gel effectively supports the 3-D culture of ovarian follicles, facilitating the maturation of functional metaphase II oocytes that can develop into blastocysts.

This study found that adult dermal papilla cells guided high-passage adult keratinocytes to produce new hair fibers, suggesting potential for large-scale hair follicle bioengineering.

In this study, researchers found that during zebrafish telencephalon regeneration, the lesioned hemisphere showed distinct gene expression changes and activated Wnt/β-catenin signaling early after injury, suggesting this pathway's significant role in recovery.

In this study, retinoic acid treatments induced glandular and feather formation in embryos by altering positional values and activating specific retinoic acid nuclear receptor gene expression.

This study found that knocking out the Hars2 gene in mouse cochlear hair cells led to mitochondrial dysfunction and ROS stress, resulting in progressive hearing loss and differential effects on inner and outer hair cells.

This study found that Fibroblast growth factor-9 (FGF-9) accelerates epithelial invagination in engineered ectodermal organs and suggests its potential role in organogenesis and regeneration research.

This study found that mouse skin can produce and metabolize serotonin and N-acetylserotonin, with activity influenced by location, physiological skin status, cell type, and mouse strain.

In this study, keratin hydrogels derived from human hair were found to significantly enhance nerve regeneration in a mouse model, acting effectively as scaffolds by influencing Schwann cell behavior.

In this study, researchers developed a chemical cocktail and suspension culture method to transform human dermal fibroblasts into dermal papilla-like cells capable of inducing hair follicle formation in vitro and in vivo.

In this study, researchers found that Sox9 is critical for determining whether Nestin⁺ stem cells in adult mouse skin develop into melanocytes or glial cells, offering insights into possible paths for melanoma research.

This study found that 3D microtissue models of dermal papilla cells can enhance the ability to induce hair-follicle neogenesis in vivo, offering potential for controlled cell production in follicle regeneration.

This review discusses how recent advances in live imaging have revealed the dynamic and adaptable nature of stem cells during various biological processes, and reports no clinical results.

This article reviews current strategies and advancements in regenerating skin appendages and sensory nerves in tissue-engineered skin, highlighting the challenge of restoring skin sensations like pain, temperature, and touch to improve patients’ quality of life.

This study found that thymus transplantation in infants with FOXN1 deficiency led to T-cell reconstitution and functional immunity, resolving serious infections and cytopenias.

In this study, researchers demonstrated that human hair follicle outer root sheath cells release ATP, serotonin, and histamine in response to mechanical stimulation, which subsequently activates surrounding sensory neurons.