research Impairment of Hair-Inducing Capacity of Three-Dimensionally Cultured Human Dermal Papilla Cells by the Ablation of STAT5
STAT5 is crucial for hair growth in 3D cultured human dermal papilla cells.
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research Skin Disease in Korean HIV Patients
HIV patients in Korea often have skin diseases like fungal infections, folliculitis, and seborrheic dermatitis, which are less common with effective HIV treatment.
research Role of Allopregnanolone Biosynthesis in Acute Stress-Induced Anxiety-Like Behaviors in Mice
Blocking allopregnanolone production in mice makes them more anxious after stress, but this can be reversed with a drug that mimics allopregnanolone.
research Nucleus-Specific Modulation of Phasic and Tonic Inhibition by Endogenous Neurosteroidogenesis in the Murine Thalamus
Brain-made chemicals can control nerve cell function differently in various parts of a mouse's brain, which may help us understand neurological conditions.
research Hair-Root Adaptation to Marasmus in Andean Indian Children
Children with marasmus have more resting hair follicles and thinner, less pigmented hair, showing long-term malnutrition.
research Linear Morphea with Evidence of Hair Regrowth
Topical treatments led to hair regrowth in a man with linear morphea.
research Identification of Drug-Specific Public TCR Driving Severe Cutaneous Adverse Reactions
Researchers found a specific immune receptor in patients that causes severe skin reactions to a drug.
research Hair Cell Toxicology: With the Help of a Little Fish
Zebrafish larvae are used to study and find treatments for ear cell damage because they are easier to observe and test than mammals.
research Abstracts from the 17th Congress of the European Society for Dermatology and Psychiatry
The congress showed that psychological therapy can help skin condition patients, social media affects acne stigma, education improves atopic dermatitis, and patient satisfaction in dermatology is high, especially with good doctor engagement.
research The Neurobiology of Sexual Function
Testosterone is important for men's sexual function, may help some women's sexual desire, while other hormones and neurotransmitters also play complex roles in sexual behavior.
research Calreticulin: Non-Endoplasmic Reticulum Functions in Physiology and Disease
Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.
research The Dynamics of the Skin’s Immune System
The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.
research Teriflunomide and Its Mechanism of Action in Multiple Sclerosis
Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.
research Timing of Expression of the Core Clock Gene Bmal1 Influences Its Effects on Aging and Survival
The timing of when the gene Bmal1 is active affects aging and survival, with its absence during development, not adulthood, leading to premature aging.
research Eph Receptors and Ephrins: Therapeutic Opportunities
Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.
research Melatonin
Melatonin may help with sleep issues, depression, and cancer, but more research is needed.
research Identification of Relay Cells and Interneurons in the Cuneate Nucleus
The cuneate nucleus has two main neuron types: relay neurons and interneurons.
research Sex Differences in the Hypothalamic–Pituitary–Adrenal Axis’ Response to Stress: An Important Role for Gonadal Hormones
Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.
research ATP-Dependent Chromatin Remodeling During Mammalian Development
ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.
research Telocytes in Human Skin – Are They Involved in Skin Regeneration?
Telocytes might help with skin repair and regeneration.
research WNT Signaling in Disease
The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.
research Ancient-Modern Concordance in Ayurvedic Plants: Some Examples
Modern science supports the use of some Ayurvedic plants for health, as ancient practices suggested.
research Periodontal Ligament Stem Cells: Regenerative Potency in Periodontium
Periodontal ligament stem cells show promise for regrowing tissues but require more research for safe, effective use.
research Targeting the Janus Kinase Family in Autoimmune Skin Diseases
Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.
research TRP Channels in Skin Biology and Pathophysiology
TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.
research Tissue Engineering and Regenerative Medicine: Achievements, Future, and Sustainability in Asia
Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.
research The Role of AUTS2 in Neurodevelopment and Human Evolution
The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.
research MIM and Cortactin Antagonism Regulates Ciliogenesis and Hedgehog Signaling
MIM is crucial for hair follicle formation and regeneration by controlling cilia formation and hedgehog signaling through its interaction with Cortactin and Src.
research Macrophages Induce AKT/β-Catenin-Dependent Lgr5+ Stem Cell Activation and Hair Follicle Regeneration Through TNF
Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.
research Targeting the Wnt Pathways for Therapies
Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.