research Tackling Underrepresentation to Aid Understanding of Parkinson’s Disease: Progress and Further Opportunities
Addressing underrepresentation in Parkinson's research is crucial for better treatments and understanding.
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research The Story of When Kidneys Fail and the Contribution of Air Vice-Marshal Sir Ralph Jackson
Air Vice-Marshal Sir Ralph Jackson significantly advanced dialysis technology in the UK.
research Structural and Functional Studies of L-PGDS and SMPDL3A Enzymes in Lipid Signaling Family
L-PGDS has specific binding sites for its functions and could help in drug delivery system design.
research Endocrinology Overview: Male Reproductive Endocrinology and HPT Axis
The document explains how male reproductive hormones work and affect the body.
research Benign Cutaneous Eruptions After Transplantation
Transplant patients often get skin problems, with treatments varying by condition.
research Glucocorticoid Receptor Antagonism Improves Glucose Metabolism in a Mouse Model of Polycystic Ovary Syndrome
Blocking glucocorticoid receptors improves glucose metabolism in a PCOS mouse model.
research Alk1 Acts in Non-Endothelial VE-Cadherin+ Perineurial Cells to Maintain Nerve Branching During Hair Homeostasis
Alk1 in specific cells is crucial for proper nerve branching and hair function.
research Reviewing and Exploring the Prospects of Platelet-Rich Plasma Therapy in Pediatric Surgical Wound Management
PRP therapy helps heal pediatric surgical wounds faster and with fewer scars but needs more research for safety and cost.
research Acne-Associated Syndromes
Acne is linked to inflammation and insulin resistance, and is associated with various syndromes that require different treatments.
research Medications
Understanding drug interactions, side effects, and patient-specific factors is crucial for effective dermatological care.
research Direct-To-Consumer Promotion of Prescription Drug Products
Drug companies were interested in advertising directly to consumers to make back their money, but most didn't think it would help and were concerned about negative effects.
research Role and Mechanisms of Phytochemicals in Hair Growth and Health
Natural products and phytochemicals may help with hair regrowth, but more research is needed.
research Diseases Of The Canine Prostate Gland
The main prostate diseases in dogs are benign growth, infections, and cancer, with various treatments ranging from drugs to surgery, but cancer treatments have limited success.
research The JAK/STAT Signaling Pathway: From Bench to Clinic
The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.
research Challenges, Progress, and Prospects of Developing Therapies to Treat Autoimmune Diseases
More precise, personalized therapies are needed for autoimmune diseases.
research Asebia-2J (Scd1ab2J): A New Allele and a Model for Scarring Alopecia
The absence of functional sebaceous glands causes hair follicle destruction and scarring alopecia.
research The Evolutionary Impact of Androgen Levels on Prostate Cancer in a Multi-Scale Mathematical Model
Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.
research Genetically Modified Laboratory Mice with Sebaceous Glands Abnormalities
Genetic changes in mice help understand skin and hair disorders, aiding treatment development for acne and hair loss.
research Myc and Fgf Are Required for Zebrafish Neuromast Hair Cell Regeneration
Zebrafish need MYC and FGF to regenerate inner ear hair cells.
research sPLA2-IIA Overexpression in Mice Epidermis Depletes Hair Follicle Stem Cells and Induces Differentiation Mediated Through Enhanced JNK/c-Jun Activation
Overexpression of sPLA2-IIA in mouse skin reduces hair stem cells and increases cell differentiation through JNK/c-Jun pathway activation.
research Cyclin D3 Deficiency Inhibits Skin Tumor Development But Does Not Affect Normal Keratinocyte Proliferation
Lacking cyclin D3 reduces skin cancer growth without affecting normal skin cell growth.
research Home Remedies in Dermatology
Many people use home remedies for skin conditions, but there's limited scientific evidence to support their effectiveness.
research Acne Syndromes and Mosaicism
Understanding how acne develops in different diseases could lead to new treatments.
research Floral Attractants in the Black Orchid Brasiliorchis Schunkeana: Clues for Presumed Sapromyophily and Potential Antimicrobial Activity
The black orchid Brasiliorchis schunkeana produces chemicals that attract certain insects and have potential antimicrobial properties.
research The Impact of Sulforaphane on Sex-Specific Conditions and Hormone Balance: A Comprehensive Review
This comprehensive review examines the effects of sulforaphane (SF), a compound from cruciferous vegetables like broccoli, on sex-specific health conditions and hormone balance. SF is noted for its antioxidant, anti-inflammatory, and cancer-preventive properties, primarily through the Keap1/Nrf2 pathway. The review highlights SF's potential in treating conditions such as cancer, neurodegenerative diseases, and cardiovascular issues, and its role in hormone-related conditions like menopause and polycystic ovarian syndrome. SF shows promise in breast and prostate cancer treatment by enhancing drug efficacy and inhibiting cancer cell growth. Additionally, SF promotes hair growth by accelerating dihydrotestosterone degradation, offering potential benefits for hair loss conditions like androgenic alopecia. The review underscores the importance of SF in maintaining hormonal balance and its potential in healthspan-enhancing practices.
research The Impact of Chemotherapy on the Nutritional Status of Breast Cancer Patients
Chemotherapy worsens nutritional status in breast cancer patients, requiring targeted nutritional strategies.
research Adipose Infiltration of the Dermis, Involving the Arrector Pili Muscle, and Dermal Displacement of Eccrine Sweat Coils: New Histologic Observations in Frontal Fibrosing Alopecia
The conclusion is that fat tissue in the skin is a new finding in Frontal fibrosing alopecia and may contribute to hair follicle and muscle degeneration.
research From the Microscopic Sweat Gland to Large Datasets: The Power of Quantitative Traits in Dermatology
Using quantitative traits in genetics can improve understanding and management of skin health and conditions.
research Commentary on Elimination of Sweat Glands Using the Follicular Unit Excision Technique
The technique removes sweat glands effectively.
research STIM1, But Not STIM2, Is the Calcium Sensor Critical for Sweat Secretion
STIM1 is essential for sweat secretion.