research Finasteride Reduces Serum PSA to a Similar Extent at 1 mg and 5 mg Daily Doses
Finasteride lowers PSA levels about the same whether taken at 1 mg or 5 mg daily.
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research Severe Physical Complications Among Survivors of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis
SJS/TEN survivors often have severe, overlooked long-term physical problems that are not properly treated after leaving the hospital.
research Immune Privilege and Alopecia Areata
Restoring immune privilege in hair follicles could help treat certain types of hair loss.
research Expression of the Orphan Protein Plet-1 During Trichilemmal Differentiation of Anagen Hair Follicles
Plet-1 protein helps hair follicle cells move and stick to tissues.
research Guadalupe Fur Seal Alopecia: A Metabolic Syndrome Associated to Climatic Anomalies?
Climate-related nutritional stress may cause hair loss in juvenile male Guadalupe fur seals.
research Penetration Profile of Microspheres in Follicular Targeting of Terminal Hair Follicles
Microspheres about 1.5 micrometers in size can best penetrate hair follicles, potentially reaching important stem cells.
research Design, Synthesis, and Preclinical Evaluation of Prostate-Specific Membrane Antigen Targeted 99mTc-Radioimaging Agents
Researchers developed promising agents for prostate cancer imaging, with the best one showing high potential for clinical use.
research Establishment of an Immortalized Mouse Dermal Papilla Cell Strain with Optimized Culture Strategy
Researchers created a long-lasting mouse skin cell strain that may help with hair growth research and treatments.
research Highly Upregulated Lhx2 in the Foxn1−/− Nude Mouse Phenotype Reflects a Dysregulated and Expanded Epidermal Stem Cell Niche
The Foxn1(-/-) nude mouse shows disrupted and expanded skin stem cell areas due to high Lhx2 levels.
research Study of Demodex Mites: Challenges and Solutions
The conclusion is that a new biopsy technique and humidity chamber help study skin mites better and suggest mite overpopulation may cause skin diseases.
research Going Below and Beyond the Surface: Microneedle Structure, Materials, Drugs, Fabrication, and Applications for Wound Healing and Tissue Regeneration
Microneedles are effective for painless drug delivery and promoting wound healing and tissue regeneration.
research Tissue Resident Foxp3+ Regulatory T Cells: Sentinels and Saboteurs in Health and Disease
Foxp3+ Regulatory T Cells are important for immunity and tolerance, affect hair growth and wound healing, and their dysfunction can contribute to obesity-related diseases and other health issues.
research Dissecting the Microenvironment Around Biosynthetic Scaffolds in Murine Skin Wound Healing
Different scaffold patterns improve wound healing and immune response in mouse skin, with aligned patterns being particularly effective.
research Follicular Targeting: A Promising Tool in Selective Dermatotherapy
Targeting hair follicles can improve skin treatments and reduce side effects.
research The CD44+ALDH+ Population of Human Keratinocytes Is Enriched for Epidermal Stem Cells with Long-Term Repopulating Ability
Certain human skin cells marked by CD44 and ALDH are rich in stem cells capable of long-term skin renewal.
research Fibronectin Connecting Cell Sheet Based on Click Chemistry for Wound Repair
Fibronectin-attached cell sheets improve wound healing and are safe and effective.
research In Vitro and In Vivo Evaluation of Biologically Synthesized Silver Nanoparticles for Topical Applications: Effect of Surface Coating and Loading into Hydrogels
Silver nanoparticles coated with substances like PEG showed strong antibacterial effects and improved wound healing when used in hydrogels.
research Antibody-Capped Mesoporous Nanoscopic Materials: Design of a Probe for the Selective Chromo-Fluorogenic Detection of Finasteride
Probe detects finasteride with high selectivity and low detection limit.
research Structural Analysis of Curly and Straight Human Hair Fibers by Scanning Microbeam SAXS
Curly and straight hair differ in how their internal fibers are arranged.
research Multiplex Matrix Network Analysis of Protein Complexes in the Human TCR Signalosome
Alopecia areata patients show unique protein activity patterns, suggesting imbalanced signaling pathways.
research Immunopathology of the Human Hair Follicle
The document concludes that immune system abnormalities cause alopecia areata, but the exact process is still not completely understood.
research Influence of Nanocrystal Size on the In Vivo Absorption Kinetics of Caffeine After Topical Application
Nanoparticles sized between 470 and 750 nm are best for delivering substances like caffeine into hair follicles for absorption.
research The Expression of Equine Keratins K42 and K124 Is Restricted to the Hoof Epidermal Lamellae of Equus Caballus
K42 and K124 keratins are only found in horse hoof lamellae.
research Comparison of Sensitivity Patterns of Direct Immunofluorescence on Perilesional Skin and Plucked Hair in Pemphigus Vulgaris
Plucked hair can help diagnose pemphigus vulgaris early.
research Poly (ɛ-Caprolactone)–Chitosan–Poly (Vinyl Alcohol) Nanofibrous Scaffolds for Skin Excisional and Burn Wounds in a Canine Model
The scaffolds significantly sped up wound healing in dogs and were safe.
research TICE Salvage Chemotherapy Treats Germ-Cell Tumors Effectively
TICE salvage chemotherapy is effective for treating germ-cell tumors with poor prognosis.
research Pemphigus Vulgaris IgG and Methylprednisolone Exhibit Reciprocal Effects on Keratinocytes
Methylprednisolone helps skin cells stick together better in pemphigus vulgaris.
research The Use of Polyethylenimine–DNA to Topically Deliver hTERT to Promote Hair Growth
Using polyethylenimine-DNA to deliver the hTERT gene can stimulate hair growth and may be useful in treating hair loss, but there could be potential cancer risks.
research Proliferative, Lymphocytic, Infundibular Mural Folliculitis and Dermatitis with Prominent Follicular Apoptosis and Parakeratotic Casts in Four Labrador Retrievers: Preliminary Description and Response to Therapy
A new skin disease in four Labrador retrievers responded well to immunosuppressive treatment.
research Gene Expression of CD70 and CD27 Is Increased in Alopecia Areata Lesions and Associated with Disease Severity and Activity
Higher CD70 and CD27 gene expression in alopecia areata lesions predicts disease severity and activity.