16 citations
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May 2020 in “Frontiers in pharmacology” This study found that minoxidil stimulates the Kir6.2/SUR2 potassium channel, leading to tumor growth arrest in an ovarian cancer xenograft model by disrupting mitochondrial function and inducing cell death.
December 2022 in “Zenodo (CERN European Organization for Nuclear Research)” This article discusses the potential benefits of Surbhi Green Tea Shampoo, including hair strengthening and increased growth, but presents no new experimental evidence supporting these claims.
June 2026 in “Ubaya Repository (University of Surabaya)” In this study, chemotherapy regimens for lung cancer in Indonesian patients were found to be guideline-congruent, but adverse effects like anemia and hair loss were common, suggesting a need for managing these to optimize treatment.
December 2024 in “Indonesian Journal of Tropical and Infectious Disease” In a tropical, high-burden region, this study found that tinea corporis and tinea cruris were the most common types of dermatophytosis, particularly affecting female adults, and that treatment commonly involved griseofulvin and ketoconazole cream, with Trichophyton mentagrophytes as the prevalent pathogen.
January 2008 in “International Journal of Trichology” This paper examines three case studies of hair disorders through the lens of analytical psychology, suggesting that psychological factors and symbolic meanings may contribute to their onset and persistence.
24 citations
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October 2012 in “The International Journal of Biochemistry & Cell Biology” In this study, testosterone protected female embryonic heart cells from metabolic stress by being converted into metabolites that activate estrogen receptors and up-regulate certain mitochondrial channel proteins.
June 2026 in “Pharmaceutical Sciences and Research” This prospective observational study in Indonesia found that chemotherapy regimens for lung cancer were 100% in line with treatment guidelines, but adverse effects, including anemia and hair loss, were common among patients, highlighting the need to consider these when optimizing treatment choices.
144 citations
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March 2013 in “Circulation Research” This study reports that mutations in the SUR2 gene are linked to Cantu syndrome, highlighting the role of KATP channels in cardiovascular health and potential new therapies.
83 citations
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December 2001 in “Journal of Investigative Dermatology” Minoxidil boosts hair growth by targeting adenosine and possibly sulfonylurea receptor 2B.
19 citations
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October 2017 in “European Journal of Pharmaceutics and Biopharmaceutics” This study found that the MXD/HP-β-CD GEL formulation promoted greater hair growth and improved gene expression related to hair growth in male rats compared to MXD solution or control groups.
7 citations
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January 2020 in “Journal of Dermatology” This study described specific skin and hair follicle abnormalities in three Japanese patients with Cantu syndrome, which may relate to the regulation role of SUR2 in hair follicle growth.
3 citations
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April 2023 in “Frontiers in Pharmacology” This study identified high expression of the Sur2A subunit in cancerous cells in two animal models, highlighting a potential drug target in breast and renal cancers, with additional pharmacovigilance data linking KATP channel genes to varied cancer risks.
1 citations
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August 2023 in “The journal of pharmacology and experimental therapeutics/The Journal of pharmacology and experimental therapeutics” This study developed a new method to analyze Cantú syndrome mutations in KATP channels, finding that while Kir6.1 mutations increase sensitivity to potassium channel openers, SUR2B mutations show reduced sensitivity, but both result in marked hyperpolarization compared to wild-type channels under basal conditions.
November 2010 in “Bradford Scholars (University of Bradford)” In this study, the authors reported that NNC55-9216, a selective SUR1 KATP channel opener, stimulated hair follicle growth in culture and enhanced the effects of minoxidil, suggesting a new potential treatment for hair loss.
13 citations
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June 2023 in “Frontiers in Molecular Neuroscience” This review suggests that blocking the ATP-sensitive potassium (K ATP) channel, particularly the Kir6.1/SUR2B subtype, may prove effective in treating migraines, with preclinical data supporting this approach; however, human studies are absent, and potential side effects could complicate clinical use.
July 2022 in “Berkala Ilmu Kesehatan Kulit dan Kelamin/Berkala ilmu kesehatan kulit dan kelamin (Periodical of dermatology and venerology)” This study reviewed medical records of tinea capitis patients at a clinic in Surabaya, finding that the condition predominantly affected young males and was often associated with contact with cats.
March 2022 in “Berkala Ilmu Kesehatan Kulit dan Kelamin/Berkala ilmu kesehatan kulit dan kelamin (Periodical of dermatology and venerology)” This study found that nearly half of the tinea capitis patients at a Surabaya hospital had cat contact, with the most common symptoms being crust and hair loss.
148 citations
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May 2012 in “The American Journal of Human Genetics” This study identified heterozygous mutations in the ABCC9 gene as the genetic basis of Cantú syndrome, suggesting the syndrome as a new member of potassium channelopathies.
January 2024 in “CRC Press eBooks” This study discusses the potential of microbial exopolysaccharides as safer cosmetic ingredients compared to synthetic chemicals like parabens and BHA, which may cause skin damage and cancer; exopolysaccharides offer benefits like antimicrobial and antioxidative effects without harmful impacts.
1 citations
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July 2020 in “Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya” This case report describes a patient with HIV who experienced overlapping symptoms of primary and secondary syphilis and showed clinical and serological improvement after treatment with benzathine penicillin and antiretroviral drugs.
July 2012 in “Ubaya Repository (University of Surabaya)” This study found that hair growth gel and tonic containing red grape seed extract were physically and chemically unstable under high temperature and humidity conditions over 30 days.
15 citations
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January 2017 in “Pigment International” This article reviews the pathogenesis and treatment approaches for premature graying of hair, noting the unsatisfactory options currently available, and reports no new clinical findings.
9 citations
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October 2012 in “PubMed” This study observed that telogen effluvium was the most common pattern of diffuse hair loss among 100 female patients, often associated with factors like stress and fever.
6 citations
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October 2016 in “Journal of Chemotherapy” This case report describes a rare instance of alopecia universalis occurring eight weeks after discontinuing pegylated interferon α and ribavirin therapy, highlighting the need for awareness among healthcare providers.
3 citations
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January 2020 in “Indian Dermatology Online Journal” In this study, significant correlations were observed between acanthosis nigricans and factors like free testosterone, DHEAS, fasting blood sugar, and BMI, as well as between hirsutism and elevated DHEAS, free testosterone, and BMI among patients with polycystic ovarian disease.
2 citations
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December 2019 in “Leprosy Review” This report describes a rare case of leprotic alopecia in a 26-year-old female, secondary to paucibacillary leprosy, with a clinical picture mimicking alopecia areata-vitiligo overlap syndrome.
2 citations
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July 2019 in “Indian dermatology online journal” This report documents a rare case of familial eyelash trichomegaly and synophrys in three siblings, with one sister also having loose anagen hair syndrome, an unreported association.
March 2026 in “World Journal of Biology Pharmacy and Health Sciences” This study developed and evaluated a polyherbal hair oil containing natural ingredients, finding that formulation F3 displayed optimal physicochemical properties and stability, suggesting its potential as a natural alternative to synthetic hair care products.
February 2026 in “Indian Dermatology Online Journal” This study reports that oral tofacitinib treatment in a patient with refractory lichen planus pigmentosus and frontal fibrosing alopecia resulted in near-complete resolution of hyperpigmentation and cessation of hairline recession over 18 months, and suggests it may be a promising therapy for these challenging conditions.
February 2026 in “Medico Research Chronicles” In this case study, a 7-year-old boy with Down syndrome and alopecia areata experienced notable hair regrowth, improved gut function, and emotional stability with individualized homeopathic treatment, whereas prior allopathic approaches were ineffective.