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The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

The document concludes that skin stem cells are important for hair growth and wound healing, and could be used in regenerative medicine.

Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.

Different types of long-lasting stem cells are responsible for the growth and upkeep of the mammary gland.

The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.

Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.

β-catenin in the dermal papilla is crucial for normal hair growth and repair.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.

Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.

Male and female skin differ in many ways, which could lead to gender-specific skin treatments.

Scientists have found a way to create hair follicles from skin cells of newborn mice, which can grow and cycle naturally when injected into adult mouse skin.

Lactate production is important for activating hair growth stem cells.

New effective scar treatments are urgently needed due to the current options' limited success.

Blood vessels and specific genes help turn cartilage into bone when bones heal.

Early development of hair, teeth, and glands involves specific signaling pathways and cellular interactions.

Too much Smad7 changes skin and hair development by breaking down a protein called β-catenin, leading to more oil glands and fewer hair follicles.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

The enzyme 25 Hydroxyvitamin D 1 α-Hydroxylase is essential for healthy skin and recovery after skin damage.

Gene therapy with the Math1 gene helped regenerate balance-related cells and improve balance in mice.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

MIM is crucial for hair follicle formation and regeneration by controlling cilia formation and hedgehog signaling through its interaction with Cortactin and Src.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

Hair, teeth, and mammary glands develop similarly at first but use different genes later.

A wearable device using electric stimulation can significantly improve hair growth.

Wnt signaling helps control how brain stem cells divide and is important for brain repair after injury.