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The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

Microemulsions could improve skin drug delivery but face challenges like complex creation and potential toxicity.

Hormone therapy improves mental well-being in transgender individuals but requires ongoing health monitoring.

Feminizing hormone therapy increases kidney filtration rate.

More research is needed to understand how testosterone is maintained in adult males.

Topical minoxidil is the best-supported treatment for female hair loss, but personalized plans are needed.

LGBT individuals have unique skin health needs, including higher STD risks and side effects from gender-affirming treatments, requiring dermatologists to offer knowledgeable and culturally competent care.

Pregnancy can cause symptoms similar to rheumatic diseases, making diagnosis difficult, and affects various body systems, requiring careful distinction between normal changes and serious conditions.

Terbinafine is the most effective medicine for fungal nail infections, especially for diabetics and those with weak immune systems.

There is no significant link between insulin resistance and certain hair disorders like idiopathic hirsutism and androgenic alopecia.

Hair loss is a common but often unreported side effect of cancer treatments, especially for breast and prostate cancers.

Hair loss is a common side effect of hormone treatments for cancer.

Hair loss is a common, often overlooked side effect of hormone treatments for breast and prostate cancer.

Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.

Pregnancy can cause skin darkening, varicose veins, more sweating, hair growth, hair loss after birth, nail changes, and gum inflammation.

Men are more likely to get infectious skin diseases, while women are more prone to autoimmune and pigment-related skin conditions, influenced by biological and environmental factors.

Safflower has been used in traditional medicine for centuries and shows promise in treating heart, brain, and inflammatory conditions, but more research is needed to ensure its safety.

The document concludes that managing skin conditions during pregnancy is important and requires specialized care.

The document summarizes medical findings on topics like heart rhythm treatment, sleep apnea therapy, and various health conditions and treatments.

Dermatologists are essential in helping transgender and gender diverse patients with skin and hair issues related to gender affirmation and hormone therapy.

The document concludes that inflammation markers can be used in diabetes, vitamin D3 affects immune pathways, hyperthyroidism changes hormone levels, androgen levels help diagnose Adrenocortical Carcinoma, erectile dysfunction is linked to diabetes, hypogonadism is common in HIV-infected males, and hormones can be biomarkers for various conditions.

Most skin changes during pregnancy are harmless and temporary, but some can risk the fetus and need careful treatment.

Stress, nutritional issues, and chronic diseases can cause hair loss, and nail changes may signal internal diseases; treatment focuses on the underlying cause.

Sublingual minoxidil effectively treats hair loss with mild side effects.

The trial showed that a new under-the-tongue treatment for severe hair loss was somewhat effective in a small group of people.

Sublingual minoxidil safely promotes hair growth.

Sublingual minoxidil is safe and well-tolerated for hair loss treatment.

Sublingual minoxidil is a safe and effective treatment for hair loss, especially in women.

Sublingual minoxidil helped regrow hair in a person with congenital triangular alopecia.

A man had a large, rare cyst in his mouth removed after 10 years, which fixed his swallowing and breathing problems.