Clinico-Epidemiological Aspects of Cutaneous Lesions in Injecting Drug Users Visiting an Oral Substitution Therapy Centre: A Cross-Sectional Study

    October 2022 in “ Dermatology practical & conceptual
    Shaminder Singh Dhillon, Tejinder Kaur, Neeru Bala, Mankaranpreet
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    Studysummary This study found that injecting drug users attending an oral substitution therapy center often experience skin lesions, which negatively impact their psychosocial health and quality of life.
    Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
    The study examined 100 injecting drug users (IDUs), with a mean age of 30.08 years, primarily males (98%) and laborers (33%). All participants abused heroin, with some also using cocaine (8%) and cannabis (3%). The mean duration of drug abuse was 8.34 years. The majority (76%) had taken their last dose of the abused drug less than a month ago. Most (99%) were being managed with buprenorphine and naloxone combination sublingual tablets. The study found that 80% were positive for hepatitis C virus (HCV) infection, 10% had HIV infection, and 9% had both HCV and HIV. Skin conditions were common, with 84% having black-colored spots and scars, 34% reporting chronic itching, and 6% having ulcers. Scabies was the most common skin disease, affecting 23 patients. Hair examination revealed trichomycosis in 2 patients, generalized sparsity in 2 subjects, and androgenetic alopecia in 1. The study also found that skin conditions had a moderate effect on quality of life in 54% of patients, with varying levels of depression, anxiety, and stress observed.
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