Hair Loss in an 11-Year-Old: Successful Treatment of Alopecia Universalis with Baricitinib and Minoxidil

    January 2022 in “ Clinical Cases in Dermatology ”
    Anneliese Willems, Rodney Sinclair
    Studysummary This case report describes the successful remission of alopecia universalis in an 11-year-old girl using combined oral Baricitinib and sublingual minoxidil, suggesting potential for similar treatments in pediatric patients.
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    Research cited in this study 10

    1. Treatment of Male and Female Pattern Hair Loss with Sublingual Minoxidil: A Retrospective Case-Series of 64 Patients Journal of The European Academy of Dermatology and Venereology · 2020
    2. Scoping Review on the Use of Drugs Targeting JAK/STAT Pathway in Atopic Dermatitis, Vitiligo, and Alopecia Areata Dermatology and therapy · 2019
    3. Treatment of Severe Alopecia Areata with Baricitinib JAAD Case Reports · 2019
    4. JAK Inhibitors for Alopecia Areata: A Systematic Review and Meta-Analysis JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology · 2019
    5. Treatment of Alopecia Areata: An Australian Expert Consensus Statement Australasian journal of dermatology · 2018
    6. Reversal of Alopecia Areata Following Treatment With the JAK1/2 Inhibitor Baricitinib EBioMedicine · 2015
    7. Alopecia Areata Is Driven by Cytotoxic T Lymphocytes and Is Reversed by JAK Inhibition Nature medicine · 2014
    8. Minoxidil Use in Dermatology, Side Effects, and Recent Patents Recent Patents on Inflammation & Allergy Drug Discovery · 2012
    9. Alopecia Areata: Diagnosis and Management International Journal of Dermatology · 1999
    10. Evaluation of Oral Minoxidil in the Treatment of Alopecia Areata Archives of Dermatology · 1987

    Related research 10

    1. Potential Herbal Medicine for Alopecia Areata Treatment: A Systematic Review International journal of research publications · 2022
    2. The Usefulness and Wellbeing of Tofacitinib in the Treatment of Alopecia Areata Journal of Armed Forces Medical College, Bangladesh · 2022
    3. The Efficacy of Azelaic Acid 20% Cream in the Treatment of Scalp Alopecia Areata المجلة العراقية للصيدلة · 2022
    4. Efficacy of Systemic Minoxidil and Tofacitinib Combination in Treatment-Resistant Alopecia Universalis Journal of Cosmetic Dermatology · 2020
    5. Hair Loss in Lichen Planopilaris and Frontal Fibrosing Alopecia: Not Always Irreversible Skin appendage disorders · 2020
    6. Remarkable Improvement of Nail Changes in Alopecia Areata Universalis with 10 Months of Treatment with Tofacitinib: A Case Report Case Reports in Dermatology · 2016
    7. Alopecia Areata: An Autoimmune Disease Causing Hair Loss Recent Patents on Inflammation & Allergy Drug Discovery · 2011
    8. Alopecia Areata: Evidence-Based Treatments Seminars in cutaneous medicine and surgery · 2009
    9. Alopecia Areata Treated With Topical Minoxidil Archives of Dermatology · 1984
    10. Topical Minoxidil in the Treatment of Alopecia Areata BMJ · 1983