January 2023 in “Open veterinary journal” This report describes the first suspected case of dermatologic adverse effects from subcutaneous furosemide in cats, noting ulcerative skin lesions that resolved after switching the formulation.
3 citations
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May 2018 in “Reproductive Sciences” In this randomized study, BAY 1158061, a prolactin receptor antibody, was found to be safe, well-tolerated, and exhibited low immunogenicity in healthy postmenopausal women, but had no effect on serum prolactin levels compared to placebo.
12 citations
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January 2018 in “Breast Cancer Basic and Clinical Research” This study reported that subcutaneous trastuzumab improved certain symptoms and did not negatively impact health-related quality of life in patients with early or metastatic HER2-overexpressing breast cancer.
9 citations
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December 1978 in “Australian Journal of Biological Sciences” This study found that flumethasone administration in Merino wethers led to variations in wool shedding and initial reductions in wool growth, with full recovery generally observed within 60 days post-treatment.
This narrative review concludes that long-term randomized controlled trials are needed to establish clear guidelines for testosterone therapy in women, given the lack of FDA-approved formulations and the variable quality of current treatments.
25 citations
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December 1991 in “The Journal of Dermatology” This study found that cyclosporin A treatment in young nude mice induced dose-dependent hair growth, which stopped after treatment cessation, but did not result in hair growth in older mice.
1 citations
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August 2021 in “Journal of Investigative Dermatology” ASLAN004 was safe and well-tolerated, supporting further development for treating certain diseases.
April 2026 in “Journal of Exercise Rehabilitation” This report describes a case where a woman's hair loss following COVID-19 vaccination improved after treatment with autologous CD34+ hematopoietic progenitor cells and umbilical cord blood-derived mesenchymal stem cells, with no significant adverse effects observed over the 12-week treatment period.
2 citations
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March 2004 in “Reviews in Gynaecological Practice” This review discusses treatments for female sexual dysfunction in postmenopausal women, noting that the effectiveness of current pharmaceutical options is inconclusive and emphasizing the importance of individualized care.
27 citations
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March 2008 in “Cell stress & chaperones” This study found that localized administration of heat or certain stress protein inducers effectively prevented chemotherapy-induced hair loss in rodent models without affecting chemotherapy efficacy.
1 citations
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November 2022 in “Journal of Cosmetic Dermatology” This review discusses the possible materials used in subcutaneous injections for alopecia, but it reports no new clinical results and highlights the need for further research.
October 1933 in “Experimental Biology and Medicine” In this study, subcutaneous injections of epinephrine in rats led to skin changes ranging from hair loss to necrosis, suggesting these effects were due to the epinephrine itself.
134 citations
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January 2010 in “Biomedical research” This study found that subcutaneous administration of conditioned medium from adipose-derived stem cells promoted hair growth in mice, and hypoxia enhanced this effect by altering growth factor secretion.
This study found that subcutaneous administration of Botulinum toxin type A significantly reduced histamine-induced itch intensity and neurogenic inflammation in human skin compared to saline.
August 2001 in “대한구강악안면외과학회지” This study found that subcutaneous administration of decorin at doses of 10 and 20 μg reduced scar formation by decreasing the thickness of immature collagen fibers in rabbit surgical wounds.
January 2025 in “Antioxidants” In this study, repetitive subcutaneous administrations of a conditioned medium from stem cells significantly suppressed hair graying in mice exposed to X-ray irradiation, likely through antioxidative mechanisms involving HGF and potentially VEGF.
6 citations
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August 2021 in “International Journal of Pharmaceutics” This study demonstrated that finasteride-loaded PLGA microspheres created using a novel microfluidic device exhibit extended drug release in beagle dogs, with modifications allowing for release up to 3 months.
In this study using C3H/HeJ mice, a single subcutaneous injection of the fusion protein PTH-CBD increased anagen hair follicle counts and promoted hair regrowth comparably to daily oral ruxolitinib, potentially by enhancing beta-catenin production and stimulating anagen transition.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, a single subcutaneous dose of PTH-CBD showed similar hair regrowth to daily oral ruxolitinib in mice with alopecia, possibly through increased beta-catenin and anagen transition stimulation.
This study reports various adverse effects associated with different doses and administration methods of a medical treatment, including gastrointestinal issues and hair loss, leading to modifications or discontinuations in some patients.
September 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that dissolving microneedle array patches containing mesoporous silica nanoparticles can deliver antigen-loaded nanoparticles into mice effectively, inducing strong immune responses similar to traditional subcutaneous injection.
May 2022 in “Research Square (Research Square)” Melatonin improved sheep reproduction, being more beneficial and cost-effective in males.
1 citations
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April 2024 in “Journal of Pharmaceutical and Pharmacological Sciences” This study evaluated androgen-induced hair loss and anagen induction mouse models, finding that Minoxidil and Pyrilutamide significantly promoted hair growth by decreasing androgen receptor protein levels and enhancing the Wnt/β-Catenin signaling pathway, supporting their use in studying novel treatments for androgenetic alopecia.
February 2023 in “Acta Scientific Women s Health” This review examines emerging and past therapies for recurrent implantation failure, focusing on three innovative strategies: PBMC, G-CSF, and PRP, but reports no new clinical results.
September 2004 in “Kitasato medical journal” This study found that a high dose of epidermal growth factor induced hair loss in sheep by causing apoptosis in anagen hair and transitioning the hair cycle to catagen.
23 citations
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July 2012 in “Calcified Tissue International” In this study, a single dose of PTH–CBD produced a sustained increase in bone mineral density for up to a year in mice, indicating its potential as an osteoporosis treatment.
3 citations
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January 2017 in “Journal of clinical and diagnostic research” This case series reported incidents of iatrogenic Cushing's Syndrome linked to high doses of intralesional corticosteroid injections and mesotherapy regimens, highlighting the need for cautious prescription practices and further research on mesotherapy safety.
1 citations
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July 2023 in “International Journal of Biological Macromolecules” In this study, researchers developed a composite paste system using minoxidil-loaded nanoparticles and valproic acid, enhanced by roller-microneedles, which significantly stimulated hair regeneration and perifollicular vascularization in an androgenetic alopecia mouse model, reducing side effects compared to traditional treatments.
1 citations
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October 2020 in “The Egyptian Journal of Histology” This study reported that ginseng had a superior therapeutic effect on benign prostatic hyperplasia in rats, showing nearly normal histological architecture compared to finasteride's incomplete restoration.
August 2022 in “Regenerative Medicine” This review discusses the potential esthetic applications and regenerative properties of adipose-derived stem cells but reports no new clinical findings, emphasizing the need for further research to establish efficacy.