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This study found that colchicine treatment significantly reduced hair fiber elongation in cultured hair follicles and altered protein expression and activity in dermal papilla cells, suggesting a role for the ubiquitin-proteasome system in its effects.

This study identified 19 genes targeted by 29 potential drugs for topical treatment of chemotherapy-induced alopecia, suggesting avenues for drug repositioning in pharmaceutical research.

This pharmacovigilance study found strong disproportionality signals suggesting an association between finasteride and Peyronie's disease-related clinical features, but the evidence does not confirm a causal link.

This study analyzed FAERS data to explore the risk and onset patterns of autoimmune skin diseases associated with immune checkpoint inhibitors, finding a strong association particularly with bullous pemphigoid and emphasizing the need for vigilant monitoring of these adverse effects.

This study found that, among COVID-19 patients in South Korea, hypertension, diabetes, and other comorbidities significantly increased mortality risk, with the age-adjusted Charlson comorbidity index being a strong predictor of death.

In this study, analysis of FDA data revealed a substantial risk of dermatologic adverse events with aromatase inhibitors, especially anastrozole and exemestane, highlighting the importance of dermatologic monitoring during such therapies.

This study identified several anticancer drugs, including vinblastine and bortezomib, that significantly increase the risk of developing chemotherapy-induced peripheral neuropathy, with variations in time-to-onset among different drug categories.

This pharmacovigilance study identified 19 drugs with high potential risk for causing male infertility, including hormonal agents, antineoplastic drugs, and antidepressants, emphasizing the need for fertility counseling and possible sperm cryopreservation in reproductive-age males before using such treatments.

This abstract raises concerns about the safety of finasteride, a medication often used for treating hair loss and prostate issues, due to emerging reports linking it to cognitive dysfunction.

This study confirms an association between TNF-α antagonist exposure and alopecia, indicating a class effect among the medications examined.

This study identified a set of tumour-suppressive microRNAs (miRNAs), termed 'normomiRs', that are highly expressed in normal tissues but low in tumors, with miR-206 and miR-381 showing significant in vitro cancer inhibition, highlighting their potential for miRNA-replacement therapies across multiple cancer types.

This study found that an age-adjusted Charlson comorbidity index of four or more strongly predicts mortality in South Korean COVID-19 patients, highlighting the impact of comorbidity burden and older age on disease severity.

This study found that isoliensinine, a natural compound identified from a database, effectively prevented stress-induced hair greying in mice by blocking β-2 adrenergic receptors on melanocyte stem cells in hair follicles.

This study found a significant association between finasteride use and reports of sexual dysfunction, particularly greater in young men using it for alopecia compared to older BPH patients.

This review summarizes the diverse pharmacological activities of papaya leaf extract, highlighting its strong medicinal properties and potential cosmetic applications, but reports no new clinical results.

This study suggests that alcohol consumption may have a less significant impact on androgenetic alopecia than previously thought, with odds ratios above 1.0 but not conclusively strong.

This study found that finasteride use was significantly associated with reports of obstructive sleep apnea and insomnia compared to other drugs in the FAERS database.

This narrative review examined the potential of hibiscus leaves and apple skin as natural ingredients for hair tonics and reported their effectiveness in addressing hair loss, highlighting properties like strong antioxidant content and ability to strengthen hair roots.

This study confirmed that methimazole use is associated with agranulocytosis, pyrexia, exposure during pregnancy, and hyperthyroidism, while also identifying new safety signals like premature birth and septic shock that require further investigation.

In this study, male-pattern baldness was strongly associated with a higher risk of keratinocyte cancers, particularly squamous cell carcinoma and melanoma, likely due to increased sun exposure on the scalp rather than androgen levels.

This study detected a significant association between finasteride use and sexual dysfunction, particularly in younger patients with alopecia, suggesting that indication and reporting stimulation may influence the observed signal.

Using hair loss drugs finasteride and dutasteride may cause sexual side effects.

This study introduced rPanglaoDB, an R package that facilitates the integration of public scRNA-seq datasets to effectively characterize rare cell types, exemplified by generating the first unbiased transcriptome profile of fibrocytes.

This system overview describes the UTokyo Repository's role in storing and providing online access to digital resources from the University of Tokyo, reporting no new empirical findings or research results.

This article discusses the MendelVar webserver, which integrates Mendelian disease data with GWAS findings to prioritize candidate genes for complex traits and reports no new experimental results.

This report describes a study of estuarine bed-sediment quality in New Jersey and New York post-Hurricane Sandy, focusing on contamination extent and potential long-term impacts, with no new findings included.

This article updates a prior work on pharmacophore modeling and highlights the advances in 3D database searching technologies for drug design, without presenting new research findings.

This study identified 30 new compounds with significant androgen receptor binding affinity through a combination of virtual screening and in vitro testing.

This study found that women with polycystic ovary syndrome have higher rates of nonalcoholic fatty liver disease, with androgen excess contributing to the risk.

This article discusses the uncertainty regarding distinct skin findings and cardiometabolic profiles among PCOS subtypes and reports no new clinical data.