Drug-Induced Male Infertility: A Real-World Study Using FAERS and EudraVigilance Databases

    January 2026 in “ Frontiers in Pharmacology ”
    Zhuozhi Gong, Jing He, Qiujian Feng … ShengJing Liu
    Studysummary This pharmacovigilance study identified 19 drugs with high potential risk for causing male infertility, including hormonal agents, antineoplastic drugs, and antidepressants, emphasizing the need for fertility counseling and possible sperm cryopreservation in reproductive-age males before using such treatments.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on public-pages-files-2025.frontiersin.org →
    Discuss this study in the Community →

    Research cited in this study 4

    1. Long-Term Use of Dutasteride to Treat Androgenic Alopecia in Young Men May Lead to Persistent Abnormalities in Semen Parameters Daehan saengsik uihak hoeji/Clinical and experimental reproductive medicine · 2025
    2. Comparative Effects of Finasteride and Minoxidil on Male Reproductive Organs: A Systematic Review of In Vitro and In Vivo Evidence Toxicology and Applied Pharmacology · 2023
    3. Testosterone Is a Contraceptive and Should Not Be Used in Men Who Desire Fertility The World Journal of Men's Health · 2019
    4. Finasteride and Male Fertility Journal of Human Reproductive Sciences · 2011