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Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.

Understanding phenotypic plasticity is crucial for developing effective cancer therapies.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Super-enhancers controlled by pioneer factors like SOX9 are crucial for stem cell adaptability and identity.

Adult stem cells from rat whisker follicles can regenerate hair follicles and sebaceous glands.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Msx and Dlx genes are crucial for development, controlling cell behaviors like growth and differentiation through their roles as gene regulators.

Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.

More dermal papilla cells in hair follicles lead to larger, healthier hair, while fewer cells cause hair thinning and loss.

Hair follicle stem cells use specific chromatin changes to control their growth and differentiation.

ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

Different types of stem cells in hair follicles play unique roles in wound healing and hair growth, with some stem cells not originating from existing hair follicles but from non-hair follicle cells. WNT signaling and the Lhx2 factor are key in creating new hair follicles.

Stem cell self-renewal is complex and needs more research for full understanding.

Keratose, derived from human hair, is a non-toxic biomaterial good for tissue regeneration and integrates well with body tissues.

Understanding hair follicle anatomy helps diagnose hair disorders.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Sonic hedgehog signaling is crucial for hair growth and maintaining hair follicle identity.

Different types of stem cells and their environments are key to skin repair and maintenance.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Scientists turned rat thymus cells into stem cells that can help repair skin and hair.

Applying a special compound can promote hair growth without harmful side effects.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

The document concludes that hair is complex, with a detailed growth cycle, structure, and clinical importance, affecting various scientific and medical fields.

Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.

A very low-calorie ketogenic diet is effective for quick weight loss and improving health in obese patients, with careful management of side effects and maintenance.

The human hair follicle can store topical compounds and be targeted for drug delivery with minimal side effects.

Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.

Traction alopecia is more common in African women than girls, especially when traction is applied to chemically relaxed hair; avoiding such hairstyles may reduce the risk.