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GI198745 is more potent and longer-lasting than finasteride, potentially better for treating hair loss.

Finasteride effectively blocks enzyme causing male pattern baldness.

5α-reductase inhibitors like finasteride may not be effective or safe for transgender individuals, and more research is needed.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Finasteride's effect on hair loss and prostate enlargement depends on its binding to an enzyme, with maximum impact at 0.2 mg dose.

Finasteride doesn't affect erections much, but may decrease libido in men.

Finasteride effectively treats enlarged prostate and male baldness, improves symptoms of hirsutism in women, but doesn't work for acne, and may delay prostate cancer progression with few side effects.

The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Low dose finasteride decreases certain steroids, possibly increasing depression risk.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.

Finasteride and dutasteride reduce unwanted movements from Parkinson's disease treatment by normalizing certain brain signals.

Finasteride and minoxidil together promote hair growth better than either alone.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

5α-reductase inhibitors help shrink the prostate, improve urinary symptoms, and may reduce prostate cancer risk.

5-alpha reductase deficiency leads to male sexual development issues and treatments like finasteride help with prostate enlargement and hair loss.

Men with male-pattern baldness have higher levels of certain testosterone metabolites and may have more active androgen metabolism.

New compounds were made that effectively block enzymes related to prostate issues and hair loss.

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

Eclipta alba extract could be a promising natural treatment for hair loss.

The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.

Some hormone-related drugs may protect brain cells in Parkinson's disease differently in men and women.

A new compound from a sponge strongly inhibits an enzyme linked to male-pattern hair loss without being toxic at low levels.

Dihydrotestosterone increases growth and spread of human brain cancer cells, and blocking its formation might help treat this cancer.

Finasteride treats baldness but may cause lasting sexual side effects.

Plant extracts like Avicennia marina, Boehmeria nipononivea, and Camellia sinensis could potentially treat hair loss with fewer side effects than synthetic drugs.

Finasteride effectively treats BPH but may increase sexual dysfunction risk.

Male pattern baldness involves hormone-related hair thinning, shorter hair, and inflammation.

Allopregnanolone is needed for certain brain processing issues caused by D1 dopamine receptor activation.

Avicennia marina extract and avicequinone C can potentially promote hair growth and treat hair loss by interfering with hair loss mechanisms and boosting growth factors.