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New genes and pathways are important for testosterone production and male sexual development.

The enzyme 17β-HSD type 2 mainly performs oxidation in human sebaceous glands, which may help protect against acne.

Testosterone therapy can help improve mood, sexual function, and bone health in women with low androgen levels, but more research is needed to establish safe and effective guidelines.

CAH is a genetic disorder affecting cortisol production and causing hormonal imbalances, with treatment and diagnosis varying by form and symptoms.

MC4R gene variants not linked to female hair loss.

Testosterone and finasteride raise insulin and zinc, lower chromium in male rats.

Cyproterone acetate may cause liver cancer at high doses, but is considered safe at recommended doses for approved uses.

Certain maturity signs appear before and after the first release of sperm in boys.

Oestrogens are key for bone growth during puberty in both boys and girls.

Pregnant women often experience skin and hair changes, with over half getting stretch marks and pigment changes, and should be cautious with cosmetic procedures due to potential risks.

The mineralocorticoid receptor may play a role in skin and hair health and could be a new target for treating related disorders.

Estrogens are key for bone growth spurts in both boys and girls and affect growth into adulthood.

Hormone therapy increases facial and body hair in transgender men, while hair removal improves well-being in transgender women, but cost is a barrier as insurance often doesn't cover it. Dermatologists can use various treatments for these hair issues.

Hormone imbalances from the pituitary, thyroid, and adrenal glands can cause infertility, but treating these disorders can improve fertility.

The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

Neurosteroids show promise for treating epilepsy and more research is needed.

Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.

5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.

The document concludes that Nonclassic Congenital Adrenal Hyperplasia requires personalized treatment plans to manage symptoms and fertility, with glucocorticoids being a common therapy.

Hormone therapy and surgeries for transgender individuals affect their skin and hair, requiring specific dermatologic treatments and respectful care.

The testosterone patch and gel are both effective, but they have different absorption patterns and effects on hormone levels.

Lovastatin doesn't improve lower urinary tract symptoms treatment.

Finasteride and dutasteride reduce neurosteroid production, possibly helping treat glioblastoma.

Dihydrotestosterone causes p27 protein breakdown in ovarian and breast cancer cells by binding with SKP2.

Androgens and SARMs play a role in body mass, frailty, skin health, and hair growth, and are used in treating prostate cancer, acne, and hair loss, with potential for new uses and improved versions in the future.

Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.

Deslorelin may help intact male dogs regrow hair from alopecia X, with a 75% success rate and no side effects.

Finasteride affects frog testes by increasing testosterone, decreasing 5α-DHT, and impacting genes related to reproduction and other functions.