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Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.

Certain pesticides and fungicides can interfere with male hormone functions, potentially causing reproductive issues in male rats.

People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Women's ovarian hormones and adrenal androgens change throughout life, affecting hair loss and health.

Copper deficiency may cause hair loss, and treating it could involve nutrition and hormones.

AGA is a genetic, hormonal hair loss treated with finasteride, minoxidil, and supplements, but new compounds are being developed.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

No clear link between finasteride use and acute pancreatitis risk.

Metformin helps reduce PCOS-related infertility by improving insulin sensitivity and inducing ovulation.

Non-classical 21 hydroxylase deficiency is an underdiagnosed cause of female hair loss and polycystic ovarian syndrome.

Baicalin may help reduce excessive male hormone levels in PCOS.

New treatments are needed for PCOS that target its genetic, hormonal, and metabolic causes.

Insulin resistance and high male hormone levels are major causes of Polycystic Ovary Syndrome.

Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.

Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Antiandrogen treatments can help with various women's health issues but often require ongoing use.

A new compound effectively inhibits human 5α-reductase 1.

Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.

Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.

Human skin produces sex hormones like estrogen and testosterone, influenced by ARO and StAR, which may affect skin elasticity and hair growth.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Diet changes hormone levels in pregnant ewes by affecting metabolism, not placental synthesis.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

High doses of testosterone disrupt hormone levels and receptor expression in the uterus, affecting fertility.

Autism's genetics are linked with early age of puberty and less hair loss, but not with hormone levels or polycystic ovary syndrome.

Postmenopausal ovary stromal cells have a unique makeup and limited steroid production, suggesting androgens come from the adrenal gland.