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The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

Human skin can make serotonin and melatonin, which help protect and maintain it.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.

Most women with excess hair growth have an underlying hormonal issue, often treated with medication and hair removal methods.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

Male pattern baldness involves genetics, hormones, and needs better treatments.

Patients with certain skin symptoms and high ANA titers should be monitored for potential systemic lupus.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Androgens have complex effects on hair growth, promoting it in some areas but causing hair loss in others, and our understanding of this is still evolving.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

Animals that change color with the seasons mainly do so in response to daylight changes, but climate change is causing camouflage problems that may require evolutionary changes.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

Oxidative stress affects hair loss in men with androgenetic alopecia.

Inherited ichthyoses cause widespread skin scaling and thickening due to gene mutations.

Lichen Planopilaris and Frontal Fibrosing Alopecia may help us understand hair follicle stem cell disorders and suggest new treatments.

New treatments for Alopecia Areata, like JAK inhibitors, show promise for hair regrowth and are likely to change future treatment approaches.

Androgenetic alopecia involves genetics, hormones, and can be treated with medications or surgery.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

The HR protein's role as a repressor is essential for controlling hair growth.

Prolactin affects when mice shed and grow hair.

Dutasteride and finasteride do not significantly affect bone density, blood fats, or blood production, but slightly lower PSA levels and minimally impact sexual function in healthy young men.