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Reduced androgens linked to kinky hair disorder and hair loss; 5a-reductase inhibitors may help.

New compounds may help treat prostate cancer by reducing cell growth.

Finasteride and minoxidil together promote hair growth better than either alone.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Researchers developed a model to predict how well certain compounds can block an enzyme related to hair loss and prostate issues, suggesting a 50 mg dose of finasteride might be effective based on lab and body data.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

The enzyme type 1 5α-reductase is more active in the hair follicle's lower part than in the skin's outer layer.

Steroid hormones are crucial for body functions and have various medical uses, but their misuse can lead to dependence.

Finasteride lowers DHT levels and raises testosterone in a dose-dependent way.

The enzyme 5α-reductase is key in causing psychotic-like effects from sleep deprivation.

The body's change of testosterone into DHT is not necessary for testosterone's muscle and sexual effects.

Testosterone and dihydrotestosterone play a role in women's health issues like excess hair and baldness, and treatments blocking these hormones may help.

Germacrene analogs, especially 8-Hydroxy germacrene B, are more effective than germacrone at blocking a hormone-related enzyme and could help treat hair loss.

Androgenetic alopecia involves genetics, hormones, and can be treated with medications or surgery.

Many treatments for hair loss lack proper testing and FDA approval, so their effectiveness is uncertain.

A new compound from a sponge strongly inhibits an enzyme linked to male-pattern hair loss without being toxic at low levels.

4-(4-Phenoxybenzoyl)benzoic acid derivatives can both increase and decrease certain types of reactive oxygen species, and may be relevant to hair loss.

Acankoreoside J from Acanthopanax koreanum may help promote hair growth.

Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.

Finasteride treats baldness but may cause lasting sexual side effects.

Plant extracts like Avicennia marina, Boehmeria nipononivea, and Camellia sinensis could potentially treat hair loss with fewer side effects than synthetic drugs.

Finasteride effectively treats BPH but may increase sexual dysfunction risk.

Finasteride blocks progesterone's effect on absence seizures in rats.

Taking oral testosterone with finasteride or dutasteride doubles testosterone levels, and food slightly affects it.

A new plant extract from Avicennia marina could potentially be used to treat common hair loss.

Male pattern baldness involves hormone-related hair thinning, shorter hair, and inflammation.

Skin changes can indicate hormonal imbalances and help diagnose endocrine disorders.

Post-finasteride syndrome causes sexual, physical, and psychological symptoms, but more research is needed to understand its causes and connection to finasteride.

Plant-based treatments can effectively and safely treat hair loss.

Men with male-pattern baldness have higher levels of certain testosterone metabolites and may have more active androgen metabolism.