Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This review discusses the role of the TMPRSS2 gene in SARS-CoV-2 infection susceptibility and outcomes, highlighting its differential expression in ethnic groups and potential as a target for COVID-19 treatments, but reports no new results.

This study reports that miR-302 promotes pluripotency by inhibiting NR2F2 and indirectly regulating OCT4 in stem cells, enhancing reprogramming efficiency when added to traditional factors.

This article reviews adverse drug reactions, emphasizes methods of prevention, and encourages reporting to the FDA's medWatch program, but presents no new study findings.

This abstract lists keywords related to various medications and therapies, but it does not provide new study results or findings.

In this study, daily treatment with angiotensin (1-7) significantly reduced disease severity in a mouse model of Systemic Lupus Erythematosus, suggesting potential for Mas agonists in future therapies.

In this study, transgenic mice overexpressing the SSAT gene were highly sensitive to polyamine analogues, leading to severe liver changes and high mortality rates after treatment.

This study found that neurosteroids can reorganize GABA A receptors in mice, mimicking ovarian cycle changes, with the process being mediated by neurosteroid levels rather than direct hormone receptor activation.

This article explores the potential mechanisms by which polydeoxyribonucleotide (PDRN) could improve skin quality, slow aging, and enhance skin regeneration, but reports no new clinical findings.

This review discusses the occurrence of persistent sexual, physical, neurological, and psychiatric side effects known as post-finasteride syndrome after 5x-reductase inhibitor treatment, and emphasizes the importance of evaluating these risks for patients with benign prostatic hyperplasia or androgenic alopecia.

This study found that S1PR1 signaling in mouse aortic endothelial cells varied by location and subtype, influencing inflammatory and lymphangiogenic gene expression through distinct molecular pathways.

This study found that 4-(ethoxycarbophenyl) retinamide (RI) exhibited significantly lower acute, subacute, and chronic toxicity compared to other retinoids in mouse and rat models.

This report details the development of a PSR™ Terminalia extract with antioxidant and anti-aging potential, highlighting its rich composition in phenolic acids, polysaccharides, and organic acids, without new clinical results.

This review discusses the similarities between COVID-19 and acute radiation syndrome, highlighting their shared inflammatory responses and suggesting that insights from radiation biology could inform COVID-19 research and treatment approaches; it reports no new clinical results.

This review discusses the management of recurrent ischemic priapism, highlighting that various treatments show differing efficacy and side effect profiles but that more research is needed to refine these strategies.

This study observed that a self-emulsifying drug delivery system for finasteride significantly enhanced bioavailability in rats compared to commercial tablets, but the formulation was found to be thermodynamically unstable.

This study found that RXRα/RARγ heterodimers are necessary for retinoic acid-induced keratinocyte proliferation in the skin, while normal epidermal maintenance does not require RAR-mediated signaling.

This article discusses the side effects of interferon beta therapy for MS, including flu-like symptoms and autoimmune reactions, and provides guidance on their management but does not report new clinical findings.

Low-dose naltrexone helps improve symptoms and stabilize frontal fibrosing alopecia and lichen planopilaris.

This study found that hydroxycinnamate derivatives, especially a compound named 10a, effectively inhibited SRD5A1 activity and protein expression in cell assays, suggesting potential for treating androgen-related conditions.

This study found that finasteride treatment in male rats led to enduring effects on depressive-like behavior, hippocampal neurogenesis and neuroinflammation, and gut microbiota composition after withdrawal.

This study describes a computational method using side-effect data from social media to identify new drug indications, suggesting it could be effective for drug repositioning.

R-spondin2 may help treat hair loss, gene differences could explain baldness, a peptide's regulation is linked to psoriasis, B-defensin gene copies may affect a skin condition's risk and severity, and potential markers and targets for alopecia areata were identified.

AI-09 is safe, effective, and reduces wrinkles for up to 6 months.

This study characterized the SARM PF-05314882, finding it demonstrates anabolic activity in rats with minimal effects on the prostate, seminal vesicles, and luteinizing hormone levels.

This study identified common and unexpected adverse events associated with ritlecitinib in real-world use, providing insights into its safety profile for treating severe alopecia areata.

This study suggests that using opioids along with 5αRI may reduce opioid use disorder risk in humans, supporting similar findings from animal studies.

This review reported that rosemary shows promise in managing ischemic stroke and other oxidative stress-related conditions due to its anti-inflammatory and antioxidant properties, highlighting its potential neuroprotective benefits for cognitive and brain health.

This study observed that conjugates of the anticancer drug raltitrexed with dextran and albumin were more cytotoxic than the free drug at high concentrations, altering cell cycle effects.

This study reports significant hair regrowth in two alopecia areata patients resistant to intralesional corticosteroids after treatment with intralesional polydeoxyribonucleotide.

This A.S.P.E.N. document offers guidance for managing parenteral nutrition shortages, emphasizing alternative routes and careful allocation to prevent deficiencies.