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Overexpression of activin A in mice skin causes skin thickening, fibrosis, and improved wound healing.

The ZIP7 gene helps control zinc levels in cells by moving zinc from the Golgi apparatus to the cytoplasm.

Metformin is effective for treating excessive hair growth in women with PCOS and may work better than the standard treatment in some ways.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Capsaicin, found in chili peppers, can slow down hair growth by affecting skin cells and hair follicles.

Demodicosis is common and often missed, needing more recognition and treatment in skin care.

Fibromodulin might help reduce scarring if increased in adult wounds like in fetal skin that heals without scars.

High androgen levels in young women with PCOS are linked to higher blood pressure.

Chitosan nanofiber scaffolds improve skin healing and are promising for wound treatment.

Early development of hair, teeth, and glands involves specific signaling pathways and cellular interactions.

The document concludes that recognizing and treating cutaneous lupus erythematosus early is crucial for managing the skin and potential systemic symptoms.

Androgens can cause hair growth in some areas and hair loss on the scalp.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

Tributyltin exposure causes sex changes, sterilization, and decline in the snail Ocinebrina aciculata, risking its extinction.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Stem cell self-renewal is complex and needs more research for full understanding.

5α-reductase inhibitors may prevent prostate cancer but could also raise the risk of more severe cancers.

The Sonic hedgehog pathway is crucial for new hair growth during mouse skin healing.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Too much androgen can cause hair loss; finasteride may help.

K6hf is a unique protein found only in a specific layer of hair follicles.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

The document recommends using both clinical evaluation and various measurement methods to assess skin greasiness, considering factors like temperature and hormones.

Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.

Human dermal fibroblasts are the main cells targeted by a virus that can cause a deadly skin cancer, and a certain inhibitor can effectively block this infection.

Different types of stem cells and their environments are key to skin repair and maintenance.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

In Italian patients with lupus, the most common skin issue was chronic cutaneous lupus, especially discoid lesions, and nonspecific skin problems occurred in about a third of those with systemic lupus, mainly during active disease.