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Rodent models helped understand psoriasis but none perfectly replicated the disease.

A new mouse hair mutation, called hague, is semidominant and unstable, but the exact cause is unknown.

The rhg mutation in mice affects the Oat gene, causing hair growth issues and other symptoms.

Human skin and hair color variation is mainly due to melanin produced by a few genes, with melanin protecting against sun damage.

Mutations in Plcd1 and Plcd3 together cause severe hair loss in mice.

Mice with too much sPLA₂-IIA have hair loss and poor wound healing due to abnormal hair growth and stem cell depletion.

The C3H/HeJ mouse model is useful for studying and testing treatments for alopecia areata.

Mice with a Gsdma3 gene mutation have thicker skin and longer hair follicle openings due to increased β-catenin levels.

A new mouse mutation causes skin and hair defects due to a gene change.

CD18-deficient mice developed psoriasis-like skin disease, useful for studying inflammatory skin disorders.

Blocking IL-17 can reduce skin inflammation in a mouse model of pityriasis rubra pilaris.

The TRPV3 gene mutation affects hair growth by keeping mice in the growth phase longer, which could help treat hair loss.

A man with kidney tumors and lung cysts was diagnosed with Birt–Hogg–Dubé syndrome and treated successfully, with genetic testing confirming the diagnosis.

The meeting highlighted the importance of genetic testing and multidisciplinary approaches in pediatric dermatology.

EPR spectroscopy showed that spontaneous hair growth results in thicker skin and less pigmented hair than depilation-induced growth.

A patient with Werner syndrome showed a range of aging-like symptoms and metabolic issues, underscoring the need for early detection and treatment.

A specific gene mutation causes long hair in Angora rabbits.

A man with hypoparathyroidism had other health issues that led to a diagnosis of a rare autoimmune disorder, APS-1.

Schizophrenia risk genes may affect early brain development, contributing to the disease.

A mutation in the Soat1 gene causes hair structure defects and other health issues in AKR/J mice.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

The document concludes that Nonclassic Congenital Adrenal Hyperplasia requires personalized treatment plans to manage symptoms and fertility, with glucocorticoids being a common therapy.

Topical drugs and near-infrared light therapy show potential for treating alopecia.

Premature graying of hair may suggest health issues and currently lacks effective treatments.

A specific gene mutation is linked to a hereditary form of dystonia that responds well to certain medications.

Skin and hair can help us understand organ regeneration, especially how certain stem cells might be used to form new organs.

A new mutation in the CYP11B1 gene was found in a woman with mild hyperandrogenemia, a rare cause of non-classic congenital adrenal hyperplasia.

The article concludes that developing in vitro models for human hair structures is important for research and reducing animal testing, but there are challenges like obtaining suitable samples and the models' limitations.

Advanced human skin models improve drug development and could replace animal testing.

The protein p53 directly reduces the production of Keratin 17, a skin and hair protein, in rats with radiation dermatitis.