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240-270 / 1000+ resultsresearch Neurogenic skin inflammation in stress‐triggered inhibition of hair growth in mice is promoted via nerve growth factor‐dependent pathways
In this study, neutralizing nerve growth factor reduced stress-triggered hair loss in mice, suggesting that nerve-immune system interactions and neurogenic inflammation contribute to this condition.
research My Clinical Experience with Needle and Laser SMP Devices
This article reviews non-surgical hair loss treatments and procedures, highlighting options like minoxidil, DHT inhibitors, and laser light therapy, and reports no new clinical findings.
research An eruption of numerous spiny papules in a pediatric transplant patient
This article discusses a journal-based CME activity on rare viral skin eruptions in pediatric transplant patients and reports no new clinical results; it aims to improve physicians' knowledge and treatment of this condition.
research 199 Impairment of notch 1 signaling is a common defect in lesions from patients with hidradenitis suppurativa
This study found that notch1 signaling is severely impaired in hidradenitis suppurativa patients with or without NCSTN or other gamma-secretase gene mutations, highlighting a canonical defect at the lesional tissue level.
research S100A6: molecular function and biomarker role
This review focuses on S100A6, a Ca²⁺-binding protein, detailing its role in cell functions, the regulation of its expression, and its potential as a biomarker and therapeutic target in various diseases.
research Cutaneous Ultrastructural Features of the Flaky Skin (fsn) Mouse Mutation
This study reports that flaky skin mice exhibit skin and nail features that closely resemble human psoriasis vulgaris, suggesting they may serve as a natural model for this condition.
research Efficacy of modern methods for assessing the severity of alopecia areata
This study found that the SBN system effectively evaluates and describes the severity and clinical variant of alopecia areata using a standardized scale, aiding in patient management and disease course prediction.
research Moth-eaten alopecia as a sole manifestation of secondary syphilis in an adolescent: Role of a dermatologist
A dermatologist helped identify syphilis in a teenager who only had hair loss.
research Transcriptome analysis reveals the genetic basis underlying the development of skin appendages and immunity in hedgehog (Atelerix albiventris)
This study found that hair-type tissues in hedgehogs show higher enrichment of immune-related genes compared to spine-type tissues, suggesting that spines evolved to protect against injuries and infections.
research LB1059 Neuromediators associated with neurogenic skin inflammation promote M2 differentiation of macrophages in human skin ex vivo
Certain substances can help skin cells become anti-inflammatory, aiding in tissue repair.
research SAÚDE MENTAL DA EQUIPE DE ENFERMAGEM NO CONTEXTO DA PANDEMIA COVID19
Nursing staff's mental health was affected during the COVID-19 pandemic.
research TRICHOSTASIS SPINULOSA OR PINSELHAAR
This article discusses a historical case of a rare skin disorder involving alopecia and follicular plugs reported in 1907; it presents no new findings.
research Spread-out Bragg peak FLASH: quantifying normal tissue toxicity in a murine model
This study found that FLASH radiation within a Spread-out Bragg Peak retained its normal tissue-sparing effect compared to conventional radiation, with a 40% reduction in acute skin damage and an 18% reduction in fibrotic development in mice.
research Clinical Snippets
R-spondin2 may help treat hair loss, gene differences could explain baldness, a peptide's regulation is linked to psoriasis, B-defensin gene copies may affect a skin condition's risk and severity, and potential markers and targets for alopecia areata were identified.
research Expression of nicastrin, NICD1, and Hes1 in NCSTN knockout mice: implications for hidradenitis suppurativa, Alzheimer’s, and liver cancer
This study suggests that the NCSTN knockout mouse could serve as an HS animal model, with tamoxifen potentially used for gene deletion in mice.
research Ophiasis Alopecia Areata in a Patient With Spondyloarthritis on Secukinumab: A Case Report and Review of the Literature
In this case report, secukinumab therapy for spondyloarthritis was associated with the development of alopecia areata in a 46-year-old woman, which improved after discontinuing the medication.
research Netherton Syndrome
This article reviews Netherton syndrome, focusing on its genetic basis, clinical presentation, and treatment options, and reports no clinical results; the authors mention potential benefits of targeted therapies and gene therapy.
research Chapter 26 Scalp Micropigmentation
I'm sorry, but I can't provide a summary without any specific details from the document.
research Effects of ginseng saponins on hair follicle growth in C57BL/6 mouse models
research Spider joint hair sensilla: adaptation to proprioreceptive stimulation
This study found that Cupiennius salei spiders have specialized mechanosensitive hairs on their legs that adaptively respond to joint movements during walking, suggesting a proprioceptive function.
research Trichostasis Spinulosa Confirmed by Standard Skin Surface Biopsy
This case report suggests that Trichostasis spinulosa should be considered in diagnosing treatment-resistant open comedone-like lesions and that skin surface biopsy might be an effective diagnostic method.
research Post-Finasteride Syndrome. Literature Review
This review examines global literature on post-finasteride syndrome, finding few studies link finasteride to rare sexual and systemic adverse effects; it is the first such review conducted in Spain.
research 503 Use of low-dose spironolactone in female pattern hair loss in a specialty alopecia clinic
In this study, low-dose spironolactone reduced the severity of female pattern hair loss in a small group of women without causing significant side effects, suggesting it may be an effective and well-tolerated treatment option.
research Topical Spironolactone in the Treatment of Ocular Graft-Versus-Host Disease
This study reported that topical spironolactone improved lid margin vascularity, corneal fluorescein staining, and disease severity scores in patients with ocular graft-versus-host disease, suggesting a potential therapeutic role by enhancing corneal lipid production with minimal adverse effects.
research Triple-Negative Sjogren’s Syndrome and Recurrent Pneumothorax: An Uncommon Presentation of Autoimmune Disease
This case report describes a rare patient with Sjogren's syndrome who experienced recurrent pneumothorax, resolved through surgical intervention, highlighting pneumothorax as an unusual complication of the condition.
research 1323 Human dermal fibroblasts and mast cell populations are altered in hidradenitis suppurativa, with epithelial-mesenchymal-transition signals ameliorated by spleen tyrosine kinase antagonism.
This study demonstrates that human epidermal stem cells can adapt to environmental temperature changes through mTOR signaling, and prolonged inhibition of mTORC1 supports stem cell maintenance, which may be vital for regenerative medicine.
research 332 FINASTERIDE FOR RECURRENT PRIAPISM IN CHILDREN AND ADOLESCENTS WITH SICKLE CELL DISEASE (SCD). REPORT OF 5 CASES
This study found that daily finasteride use appears to reduce the frequency of recurrent priapism in children and adolescents with sickle cell disease, with no side effects observed during a short-term follow-up.
research Cutaneous application of α-methylspermidine activates the growth of resting hair follicles in mice
In this study, topical application of α-methylspermidine during the telogen phase in mice induced hair growth by increasing the polyamine pool and mimicking the anagen phase's characteristics.
research Abstract 1835: Development of mammary hyperplasia, dysplasia, and invasive ductal carcinoma in transgenic mice expressing the 8p11 amplicon oncogene NSD3 (WHSC1L1)
This study found that overexpression of NSD3 in the mammary gland of transgenic mice led to mammary hyperplasia, dysplasia, and invasive ductal carcinoma, mirroring patterns seen in human breast cancer.