Use of Low-Dose Spironolactone in Female Pattern Hair Loss in a Specialty Alopecia Clinic

    April 2023 in “ Journal of Investigative Dermatology ”
    S. Devjani, O. Ezemma, K.J. Kelley, M.M. Senna
    TLDR Low-dose spironolactone effectively treats female pattern hair loss with mild side effects.
    A retrospective chart review of 14 adult women with female pattern hair loss (FPHL) treated with low-dose spironolactone (≤50mg daily) at a specialty alopecia clinic showed promising results. The average age of participants was 59 years, and the majority were Caucasian. The average Sinclair scale score decreased from 2.64 to 2.11 after approximately 1 year of treatment. Mild side effects such as breast tenderness, dizziness, nausea, and increased urination were reported but did not lead to discontinuation. No cases of hyperkalemia were observed. The study suggests that low-dose spironolactone is an effective and well-tolerated treatment for FPHL, particularly for patients who cannot tolerate higher doses. Further large-scale studies are recommended to confirm these findings.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 343 results

      community For the ladies: Spironolactone for FPHL

      in Female  12 upvotes 7 years ago
      A 34 year old female with androgenic alopecia who has tried treatments such as Spironolactone, Desogen, Minoxidil and Finasteride in order to address her hair loss. It also details the experiences of other women taking Spironolactone for Female Pattern Hair Loss (FPHL).

      community Spironolactine Update: 2 months (34, Female)

      in Female  23 upvotes 7 years ago
      A female user's experience using Spironolactone to treat Female Pattern Hair Loss (FPHL) and Androgenic Alopecia, as well as discussing the effectiveness of the drug at different dosages.

      community Spironolactone Update

      in Female  11 upvotes 7 years ago
      A woman's experience with Spironolactone as treatment for female pattern hair loss, including the effects of increasing dosage and her doctor's recommendation to try finasteride if no results are seen after 6 months. Other users have also shared their experiences with using finasteride for this condition.

      community bicalutamide or spironolactone for fphl

      in Female  6 upvotes 2 years ago
      Bicalutamide and spironolactone are being compared for their effectiveness and safety in treating female pattern hair loss. The conversation seeks advice on which is better to use.

      community Finasteride 5mg for female pattern hair loss

      in Female  7 upvotes 4 years ago
      The user's experience of using Finasteride 5mg and Aldactone 50mg to treat Female Pattern Hair Loss, as well as their use of PRP injections for further hair growth.

      community Low iron and hair loss connection

      in Female  16 upvotes 6 months ago
      A 39-year-old woman noticed hair thinning and found she has an iron deficiency, which may be linked to hair loss. Suggestions included seeing a dermatologist, using spironolactone, and minoxidil.

    Related Research

    8 / 8 results