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This study found that spleens of black C57BL/6 mice contain eumelanin, with properties different from skin and hair melanin, and may originate from skin melanin transported by immune cells.

This study found that splenic melanosis in C57BL/6 mice is associated with synchronized skin melanization during hair cycles, but decreases with age.

This study reports on three cases where Shengyang Sanhuo Decoction, a traditional treatment, was used to address alopecia by supporting spleen and stomach health, as theorized to counteract causes like emotional stress and improper diet.

In this study, Chinese comprehensive therapy was found to effectively improve symptoms and promote hair growth in individuals with androgenetic alopecia of a specific traditional Chinese medicine pattern.

This case study reports the first known instance of adult Kawasaki's disease presenting with highly elevated serum ferritin levels and splenomegaly, emphasizing its consideration in differential diagnoses for adults with persistent rash, fever, and specific clinical features.

In this study, researchers found that cyclophosphamide treatment unexpectedly reduced splenic melanin deposition in a murine model, whereas this effect was down-regulated more by the normal and dystrophic catagen phase of the hair cycle.

In this study, bezafibrate treatment improved certain aging-like features in a mouse model with mitochondrial dysfunction, but did not enhance muscle function or lifespan.

This case study describes an 85-year-old man's intermittent fever being ultimately diagnosed as Babesia infection after considering his travel history and diagnosing splenic infarcts, highlighting the importance of thorough patient history for accurate diagnosis.

This study found that intrathymic injection of recipient-type splenocytes into donor rats, combined with antilymphocyte antiserum, effectively prevented graft-versus-host disease for up to 300 days.

This study demonstrates that human epidermal stem cells can adapt to environmental temperature changes through mTOR signaling, and prolonged inhibition of mTORC1 supports stem cell maintenance, which may be vital for regenerative medicine.

This study found that high-dose Cyclosporin A in rats led to significant functional and structural changes, including liver, kidney, and immune system alterations, along with behavioral and hematological effects.

In this study, a group taking compound ginseng cicada decoction showed significantly lower relapse rates, severity, and itching related to atopic dermatitis over 3 months compared to a control group, and reported improved quality of life with no significant adverse events.

This study reports the first successful use of zanubrutinib to treat a 15-year-old Chinese girl with severe refractory Evans' syndrome, resulting in a sustained recovery of platelet counts and haemoglobin levels.

This paper discusses Professor WEI Yue-gang's approach to treating androgenetic alopecia with Traditional Chinese Medicine and reports no new clinical results.

This review discusses the combined use of plum-blossom and Daoma needle therapy for androgenic alopecia, emphasizing its potential benefits and the need for further clinical research, but reports no new results.

In this analysis, Professor Ma Shuanquan attributes androgenetic alopecia to liver, spleen, and kidney dysfunctions and describes a treatment approach using Chinese medicines focused on these organs, suggesting individualization and noting significant therapeutic effects.

This paper introduces the clinical efficacy of a modified Renshen Yangrong Tang formula for treating viral hepatitis, insomnia, hair loss, and prolonged menstrual periods, emphasizing its application for qi and blood deficiency.

This study found that dermal injection of M-CSF stimulated CD11b + myeloid cells can induce alopecia areata in mice by potentially activating B lymphocytes, offering insight into the disease's pathogenesis.

This study reports that systemic lupus erythematosus patients with Evans syndrome often exhibited photosensitivity, hypocomplementemia, and elevated serum IgG, while lupus nephritis was less common, suggesting distinct clinical features.

This study found that androgens decreased splenic macrophage FcgammaR expression and impaired the clearance of IgG-coated cells in an experimental guinea pig model.

This study observed that extracts of Biotae Orientalis showed hair growth effects in mice and suggest they may be useful for topical treatment of alopecia areata.

In this study, researchers reviewed various traditional herbal remedies, such as Tribulus terrestris and Matricaria chamomilla, focusing on their global medicinal use and discussing some of the chemical components that contribute to their biological activity.

This study reports that in mice, CD11b+ myeloid cells can convert into epithelial cells, contributing to skin wound repair and hair follicle regeneration.

This study found that gentamicin-loaded exosomes derived from bovine leukocyte spleen extract enhanced antimicrobial activity and promoted tissue regeneration in infected diabetic mouse wounds, suggesting a potential innovative therapeutic strategy for diabetic foot ulcers by combining infection control with pro-regenerative and immunomodulatory effects.

This case report describes a 65-year-old man diagnosed with atraumatic splenic rupture, which is rare and can occur without trauma, following sudden-onset left-sided abdominal pain.

In this study, researchers found that gentamicin-loaded exosomes derived from a bovine leukocyte spleen extract significantly enhanced antimicrobial activity and tissue regeneration in infected diabetic wounds, showing potential as an effective therapeutic strategy for diabetic foot ulcers by improving infection control and promoting healing.

In this study, gentamicin-loaded exosomes from a bovine leukocyte spleen extract were found to enhance tissue regeneration and antimicrobial activity, offering a promising therapeutic approach for infected diabetic foot ulcers by promoting wound healing and modulating inflammation in a diabetic mouse model.

This article reports the first case of group B streptococcal meningitis in an HIV-positive patient who had previously undergone a splenectomy.

In this study, PEGDE above 10,000 μg/mouse caused subcutaneous toxicity including ulceration in mice, but did not affect liver, spleen, or kidney tissues.

This study found that zinc content decreases not only in the blood but also in other tissues like the heart, spleen, liver, and kidney of carcinoma patients.