Gentamicin-Loaded Exosomes From Immunepotent CRP Enhance Healing Of Infected Diabetic Wounds In Mice

November 2025 in “ OPAL (Open@LaTrobe) (La Trobe University) ”

Paola Leonor García Coronado (18582106), Brandon Alberto Garza Martínez (22695917), Kenia Arisbe Moreno Amador (22695920), David Reding Hernández (22695923), Diana G. Zárate Triviño (22695926), Diana Elia Caballero Hernández (22695929), Pablo Zapata Benavides (18582121), Gabriel Luna Barcenas (22695932), Cristina Rodríguez‐Padilla (22695935), Moisés Armides Franco Molina (18582109)

gentamicin exosomes collagen deposition hair follicle regeneration pro-inflammatory cytokines anti-inflammatory IL-10

Studysummary In this study, gentamicin-loaded exosomes from a bovine leukocyte spleen extract were found to enhance tissue regeneration and antimicrobial activity, offering a promising therapeutic approach for infected diabetic foot ulcers by promoting wound healing and modulating inflammation in a diabetic mouse model.

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