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research Topical imiquimod—Be aware of the unexpected
A woman had a severe skin reaction from the drug imiquimod, used for skin cancer, highlighting the need for awareness of rare but serious side effects.
research Simultaneous Versus Delayed Initiation of Spironolactone and Low‐Dose Oral Minoxidil: Adverse Event Rates in a Retrospective Cohort Study
This article discusses the availability of data from TriNetX for research purposes and reports no new findings.
research Impaired LEF1 Activation Accelerates iPSC-Derived Keratinocytes Differentiation in Hutchinson-Gilford Progeria Syndrome
This study found that in Hutchinson–Gilford progeria syndrome, iPSCs committed to the keratinocyte lineage faster than normal cells, with LEF1 expression reduced and a partial rescue of the phenotype achieved through adenine base editing.
research FLIM Reveals Red Light-Induced Changes in Murine Hair Follicles
In this study, red-light irradiation significantly increased hair follicle numbers and ATP levels in a mouse model, highlighting low-level laser therapy's potential to enhance hair regeneration and alter the skin metabolic microenvironment.
research Scalp Micropigmentation
research 289 Immortalization of primary human dermal papilla cells by Bmi-1 and TERT
This study reported that introducing the TERT and Bmi1 genes into mouse dermal papilla cells resulted in immortal cells capable of inducing new hair follicles in vivo, and human immortal DPCs were also developed.
research ISID0199 – Computer vision AI-based androgenetic alopecia analysis using a novel mobile web app.
research 보문 : 마우스에서 하수오 열수추출물이 발모관련 효소활성과 유전자 발현에 미치는 영향
This study observed that Polygoni mulitiflori Radix water extracts accelerated hair regrowth in mice by enhancing enzyme activities and increasing IGF-1 gene expression related to hair growth.
research 458 UVB-induced facultative pigmentation is associated with distinct DNA methylation changes
This study found that UVB exposure led to visible tanning and distinct DNA methylation changes in pigmentation genes in tan-capable skin but not in non-tan skin, highlighting GNAS as a potentially UVB-responsive gene.
research Panax notoginseng saponins promote hair follicle growth in mice via Wnt/β‐Catenin signaling pathway
This study found that 8% Panax notoginseng saponins may promote hair follicle growth in C57BL/6J mice, potentially through the Wnt/β-catenin signaling pathway.
research Transgenic Immortalization of Human Dermal Fibroblasts Mediated Through the MicroRNA/SIRT1 Pathway
In this study, researchers found that hTERT/SV40 immortalization of human dermal fibroblasts up-regulates skin cell markers and highlights the SIRT1 and miR-93 pathways' roles in maintaining fibroblast proliferation, potentially benefiting developments in the cosmetic industry.
research Efficacy and Safety of a Proprietary Free Fatty Acid Rich Saw Palmetto Extract (USPlus® PRO) for Lower Urinary Tract Symptoms in Males: A Randomized, Double-Blind, Placebo-Controlled Trial
This randomized, placebo-controlled trial reported that USPlus PRO saw palmetto extract significantly improved lower urinary tract symptoms, including voiding, incomplete emptying, and weak stream, as well as sexual function in males over 12 weeks, while maintaining a favorable safety profile.
research CLINICAL EVALUATION OF A TRICHOLOGICAL PHYTOEXTRACT PRODUCT IN ANDROGENETIC ALOPECIA
This study found that 54% of participants with androgenetic alopecia using Ricapil® showed clinical signs of hair follicle reactivation and initial hair regrowth over three months.
research Combining Scalp Micropigmentation (SMP) and Hair Transplantation
This publication lists the contributors and affiliations for a research piece but reports no study results or findings.
research Molecular mechanisms of root hair growth induced by Pi deficiency in Brassica carinata
research Successful Management of Netherton Syndrome Using IVIG and Dupilumab: A Case Report
In this case report, a 7-month-old boy with Netherton syndrome experienced significant improvement in symptoms, including reduced pruritus and increased hair growth, through a combination of intravenous immunoglobulin and dupilumab treatment, which also decreased high serum IgE levels and food-specific IgE antibodies.
research Screening of Sheep Fibroblast Cell Line with the Spider Dragline Silk Protein Gene
In this study, researchers successfully established a stable transgenic sheep fibroblast cell line containing an artificially synthesized spider dragline silk protein gene.
research Development of Indian Council of Medical Research (ICMR) Standard Treatment Workflows for Skin Diseases: A Step Toward Universal Health Coverage
This study developed and finalized standard treatment workflows for thirteen common skin diseases, such as acne, eczema, and psoriasis, to optimize management across primary, secondary, and tertiary care centers in the country, with resources available both online and in physical formats.
research Isolation and Cultivation of Skin-Derived Precursors
This paper describes a protocol for isolating and culturing skin-derived precursors to potentially induce hair growth and regenerate hair follicles, but reports no new experimental findings.
research 545 Skin Organoids derived from NCSTN mutated patient-induced pluripotent stem cells recapitulate Hidradenitis Suppurativa pathogenic hallmarks
This study found that skin organoids derived from iPSCs with an HS-associated NCSTN mutation showed defects in hair follicle stem cell differentiation and increased expression of inflammatory proteins related to hidradenitis suppurativa.
research Electron paramagnetic resonance (EPR) spectroscopy for investigating murine telogen skin after spontaneous or depilation-induced hair growth
This research found that spontaneous and depilation-induced hair growth result in biologically distinct telogen phases in murine skin, with variations in thickness, pigment content, and hair follicle composition.
research New multi-targeting strategy in hair growth promotion: in vitro and in vivo studies
In this study, using a lotion containing N1-methylspermidine and Sandalore® for 3 months significantly reduced hair loss and stimulated hair growth in both men and women with chronic telogen effluvium, with benefits persisting 3 months after treatment ended.
research Insights into the regeneration of skin from Acomys , the spiny mouse
This review explores the skin regeneration process in spiny mice and highlights differences from laboratory mice, focusing on potential molecular and immune system roles without reporting new experimental results.
research President's Message
This overview discusses the educational priorities and resources of the International Society of Hair Restoration Surgery, including their publication and annual meeting, but presents no new findings.
research Great Expectations: Induced pluripotent stem cell technologies in neurodevelopmental impairments
This article reviews the development and use of induced pluripotent stem cell models and artificial organoids for studying neurodevelopmental disorders, but it reports no new clinical findings.
research Uji Aktivitas Sitotoksik Ekstrak Etanol dan Metanol Spirulina platensis L. terhadap Sel WiDr
This study found that ethanol and methanol extracts of Spirulina platensis did not exhibit cytotoxic activity on WiDr colon cancer cells.
research The IVIG treatment response in autoimmune polyendocrine syndromes type 2 with anti-GAD65 antibody-associated stiff person syndrome: a case report and literature review
This case report details a rare instance of a young male with coexisting autoimmune polyendocrine syndrome type 2 and anti-GAD65 antibody-associated stiff person syndrome, where symptoms improved by adding intravenous immunoglobulin therapy, emphasizing the importance of awareness for early diagnosis and treatment.
research Epidermal Cells Expressing Putative Cell Markers in Nonglabrous Skin Existing in Direct Proximity with the Distal End of the Arrector Pili Muscle
This study found that epidermal stem cells in nonglabrous skin are connected to the distal end of the arrector pili muscle, which may play a role in epidermal renewal and wound healing.
research 1619 Spatial transcriptomic analysis of imiquimod-treated mouse skin reveals deregulation of lipid raft-associated markers which could be reversed by re-introduction of caveolin scaffolding domain peptide
This study suggests that caveolin-1 may be a potential target for treating psoriasis, as its downregulation was linked to psoriasis markers that improved with soluble caveolin scaffolding domain peptide treatment.