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The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Researchers found four key proteins that affect the development of a specific hair type in Yangtze River Delta white goats.

Hypothyroidism harms rat skin, but topical triiodothyronine may help improve it.

Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.

Androgens can cause hair growth in some areas and hair loss on the scalp.

Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.

Various treatments exist for hair loss, but more research is needed for better options.

Genetic factors affect hair loss, and molecular testing may help predict, diagnose, and treat it.

Melatonin treatment may increase cashmere production in Spanish goats.

Hair transplantation for men has improved, offering natural, lasting results, and may be enhanced by certain medications and future technologies.

Finasteride-loaded ethosomes improve hair loss treatment by targeting pilosebaceous unit.

Phthirusa pyrifolia extract may lower testosterone and harm male rat reproduction without damaging the liver or kidneys.

PNKP is essential for keeping adult mouse progenitor cells healthy and growing normally.

Stem cells regenerate tissues and their behavior varies by environment, suggesting the hematopoietic system model may need revision.

Exposure to certain sex hormones can increase health risks, while some hormone therapies may offer benefits for specific conditions.

The document discusses male and female pattern hair loss, its diagnosis methods, FDA-approved treatments like finasteride and minoxidil, their side effects, and the role of lifestyle changes.

Activating the GDNF-GFRα1-RET signaling pathway could potentially promote skin and limb regeneration in humans and could be used to treat hair loss and promote wound healing.

Finasteride harms Daphnia magna's reproduction, growth, and metabolism.

Men with early hair loss have similar hormone levels to women with PCOS, possibly increasing risk of obesity and heart issues.

Brothers of women with PCOS tend to have higher levels of a hormone called DHEAS, indicating a possible genetic link.

Hormonal imbalances are important in the development of male pattern baldness.

Early hair loss in men may signal broader health issues similar to PCOS in women.

Oral retinoids are effective for severe skin conditions but require careful use due to side effects.

Finasteride doesn't harm male fertility or sperm quality, but may slightly reduce ejaculate volume.

Finasteride exposure harms tadpole reproduction and hormone balance.

Finasteride doesn't change rat testicle weight or sperm production.

Finasteride 1-mg doesn't harm sperm or pregnancy chances.

Finasteride, at doses of 5mg or higher, may negatively affect male fertility by reducing the expression of certain genes involved in sperm production.

Clomiphene citrate improves fertility in men taking finasteride for hair loss.