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The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

Some treatments can help with hair regrowth in alopecia areata, but results vary and long-term use is often needed without changing the disease's outcome.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Longer CAG repeat lengths in the androgen receptor gene are linked to higher testosterone levels in women with PCOS.

Current and future treatments for alopecia areata focus on immunosuppression, immunomodulation, and protecting hair follicles.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

GLI2 increases follistatin production in human skin cells.

Three drugs change mice's alcohol drinking patterns by affecting GABAA receptors.

Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.

5-alpha-reductase inhibitors may cause a low incidence of erectile dysfunction that decreases over time.

Polyamines are important for hair growth, but more research is needed to understand their functions and treatment potential.

Finasteride can cause one-sided breast enlargement, which disappears after stopping the drug.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

The document concludes that accurate diagnosis and treatment of scalp itch require differentiating between various conditions using a proposed five-step evaluation process.

Women with PCOS have higher levels of AMH in their blood and follicles, and this can help predict their risk of overreaction to fertility treatments.

Safflower has been used in traditional medicine for centuries and shows promise in treating heart, brain, and inflammatory conditions, but more research is needed to ensure its safety.

Women with PCOS have higher xanthine oxidase activity linked to inflammation and heart disease risks.

17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.

Topical contact sensitizers can treat certain skin conditions but are rarely used in the U.K.

The medications 5α-reductase inhibitors and spironolactone are generally safe for breast cancer patients on endocrine therapies and do not significantly increase breast cancer risk.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

Rumex japonicus Houtt. may be an effective treatment for atopic dermatitis by reducing inflammation.

Dutasteride works better than finasteride for hair loss, with both being safe to use.

New treatments and early diagnosis methods for permanent hair loss due to scar tissue are important for managing its psychological effects.

Hair's structure and properties change with pH; acidic pH maintains strength and less swelling, while alkaline pH increases water content and swelling.

Testosterone and dihydrotestosterone have similar effects on body composition and metabolic health in men.

Post-finasteride syndrome's existence is uncertain; more research needed.

The length of CAG repeats in the androgen receptor gene is linked to ovarian reserve but does not affect how the ovaries respond to stimulation.

People with lupus and rheumatoid arthritis have thinner hair than healthy people.

Men, particularly those with hair loss, are more likely to get the virus, and those with prostate cancer may have milder symptoms. Testosterone's role in the disease is unclear, and the virus doesn't seem to harm male fertility. Women with PCOS might be at higher risk. More research is needed.