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research Dynamic and Spatial Transcriptional Responses in COVID-19-Related Chilblains
COVID-toes show a unique immune response over time, different from vaccine-related chilblains.
research Temporal-Spatial Activation of Wnt-Signaling Within Type 1 and Type 2 Immunity During Wound Healing
Wnt-signaling is regulated differently in skin cells and immune responses during wound healing.
research Ex Vivo SIM-AFM Measurements Reveal the Spatial Correlation of Stiffness and Molecular Distributions in 3D Living Tissue
Collagen makes skin stiff, and preservation methods greatly increase tissue stiffness.
research Hair Analysis Based on Medical History and Spatial-Temporal Data
Hair analysis can provide insights into a person's medical history and location over time.
research Deciphering a Message from the Nucleus: How Transcription Factors and Spatial Chromatin Interactions Orchestrate Epidermal Differentiation
Key skin cell regulators and gene organization changes are crucial for skin cell development and could help treat skin disorders.
research Influence Of Selenium Supplementation On Mercury Levels In Hair Of Metropolitan Residents In China: Spatial Distribution, Impact Factors, And Antagonism
Selenium supplements may reduce mercury levels in the hair of city dwellers in China.
research RY-023, an Inverse Agonist at Alpha5 GABAA Receptors: The Influence on Spatial Memory and Spontaneous Locomotor Activity
RY-023, a specific drug, can improve early stage memory learning without affecting general activity in rats, but it's less effective for later learning stages and doesn't impact memory recall.
research Untargeted Scanning of Hair for Drugs of Abuse by Direct Analysis in Real Time–High-Resolution Mass Spectrometry
A new method can quickly and accurately detect drugs in hair.
research Mapping Human Skin: One Sequenced Cell at a Time
The article concludes that creating a detailed map of normal human skin at the single-cell level is important.
research Ligand-Dependent Wnt Signaling Attenuates Mechanotransduction and Protects Against Wound Occlusion-Mediated Abolishment of Hair Follicle Regeneration
Covering a wound can stop hair growth by promoting scarring, but boosting a process called Wnt signaling can help hair grow back even when the wound is covered.
research Double-Wavelength Laser Scanning Microphotometer for In-Vitro Hair Shaft and Surrounding Tissue Imaging
The DWLSM provides detailed imaging of hair shafts and follicles with high accuracy.
research Androgens Protect Against Apolipoprotein E4-Induced Cognitive Deficits
Androgens can help prevent memory problems caused by apoE4.
research Non-Invasive Evaluation of Hair Interior Morphology by X-Ray Microscope
X-ray microscopy can non-invasively show hair structure changes after treatments, but it's less detailed than TEM and needs improvement.
research The Developmental Basis of Fingerprint Pattern Formation and Variation
Fingerprints form uniquely before birth due to specific genetic pathways and local signals.
research Modeling Cell-Cell Communication for Immune Systems Across Space and Time
The document concludes that computational models are useful for understanding immune responses and could improve cancer immunotherapy.
research Ex-Vivo Measurement of Scalp Follicular Infundibulum Delivery of Zinc Pyrithione and Climbazole from an Anti-Dandruff Shampoo
The method shows that zinc pyrithione and climbazole from anti-dandruff shampoo effectively reach the scalp.
research Balint’s Syndrome—Missed or Mistaken?
The document concludes that early diagnosis of Balint's syndrome is crucial for effective treatment and that understanding drug interactions, like between ritonavir and statins, is important for patient care.
research Col4a2-eGFP Mouse Model Reveals the Molecular and Functional Dynamics of Basement Membrane Remodelling in Hair Follicle Morphogenesis
Scientists made a mouse that shows how a specific protein in the skin changes and affects hair growth and shape.
research Responses of Hair Follicle–Associated Structures to Loss of Planar Cell Polarity Signaling
Loss of Fz6 disrupts hair follicle and associated structures' orientation.
research Upregulation of Interfollicular Epidermal and Hair Infundibulum β-Catenin Expression in Gsdma3 Mutant Mice
Mice with a Gsdma3 gene mutation have thicker skin and longer hair follicle openings due to increased β-catenin levels.
research Patient-Level Adverse Event Patterns in a Single-Institution Study of the Multi-Kinase Inhibitor Sorafenib
Sorafenib often causes mucositis, hand-foot syndrome, rash, alopecia, diarrhea, and fatigue.
research Monitoring Spatially Resolved Trace Elements in Polar Bear Hair Using Single Spot Laser Ablation ICP-MS
Laser ablation ICP-MS is effective for tracking trace elements in polar bear hair over time.
research Human Hair Keratin-Based Hydrogels in Regenerative Medicine: Current Status and Future Directions
Human hair keratin hydrogels show promise for use in regenerative medicine.
research Efficient Generation of Skin Organoids from Pluripotent Cells Using Defined Extracellular Matrix Cues and Morphogen Gradients in a Microfluidic Device
Scientists developed a new way to create skin-like structures from stem cells using a special 3D gel and a device that improves cell organization and increases hair growth.
research Development of Hair Analysis Methods by MALDI-TOF-MS and MALDI-MSI and Evaluation of Cosmetic Treatments
The study concluded that the developed method can show how argan, avocado, and coconut oils penetrate and change hair, suggesting these oils are effective in hair treatments.
research Oncogenic Kras Induces Spatiotemporally Specific Tissue Deformation Through Converting Pulsatile Into Sustained ERK Activation
The Kras mutation changes normal cell signals, leading to disrupted tissue structure and potential cancer.
research Oncogenic Ras Mutation Induces Spatiotemporally Specific Tissue Deformation Through Converting Fluctuated Into Sustained ERK Activation
A specific mutation in Kras causes abnormal tissue changes by making a cell signal continuously active, which disrupts normal cell coordination.
research Mapping the Molecular and Structural Specialization of the Skin Basement Membrane for Inter-Tissue Interactions
The skin basement membrane is specialized for different tissue interactions, important for hair growth and attachment.
research Single Cell Transcriptome Profiling of Human Interfollicular Epidermis Reveals Robust Heterogeneity and Divergent Differentiation Lineages
The human skin's outer layer has more variety in cell types and development paths than previously thought.